Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia

Toll-like Receptor 4, Osteoblasts and Leukemogenesis; the Lesson from Acute Myeloid Leukemia

Toll-like receptor 4 (TLR4) is a pattern-recognizing receptor that can bind exogenous and endogenous ligands. It is expressed by acute myeloid leukemia (AML) cells, several bone marrow stromal cells, and nonleukemic cells involved in inflammation. TLR4 can bind a wide range of endogenous ligands tha...

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Bibliographic Details
Main Authors: Øystein Bruserud, Håkon Reikvam, Annette Katharina Brenner
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
toll-like receptor 4
osteoblast
mesenchymal stem cells
adipocyte
bone marrow
inflammation
Online Access:https://www.mdpi.com/1420-3049/27/3/735

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