Nanomaterial Shape Influence on Cell Behavior
Nanomaterials are proven to affect the biological activity of mammalian and microbial cells profoundly. Despite this fact, only surface chemistry, charge, and area are often linked to these phenomena. Moreover, most attention in this field is directed exclusively at nanomaterial cytotoxicity. At the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/10/5266 |
| _version_ | 1797533801365110784 |
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| author | Daniil V. Kladko Aleksandra S. Falchevskaya Nikita S. Serov Artur Y. Prilepskii |
| author_facet | Daniil V. Kladko Aleksandra S. Falchevskaya Nikita S. Serov Artur Y. Prilepskii |
| author_sort | Daniil V. Kladko |
| collection | DOAJ |
| description | Nanomaterials are proven to affect the biological activity of mammalian and microbial cells profoundly. Despite this fact, only surface chemistry, charge, and area are often linked to these phenomena. Moreover, most attention in this field is directed exclusively at nanomaterial cytotoxicity. At the same time, there is a large body of studies showing the influence of nanomaterials on cellular metabolism, proliferation, differentiation, reprogramming, gene transfer, and many other processes. Furthermore, it has been revealed that in all these cases, the shape of the nanomaterial plays a crucial role. In this paper, the mechanisms of nanomaterials shape control, approaches toward its synthesis, and the influence of nanomaterial shape on various biological activities of mammalian and microbial cells, such as proliferation, differentiation, and metabolism, as well as the prospects of this emerging field, are reviewed. |
| first_indexed | 2024-03-10T11:20:47Z |
| format | Article |
| id | doaj.art-313888238fb34dbba07d3f969b5177e3 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T11:20:47Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-313888238fb34dbba07d3f969b5177e32023-11-21T20:04:01ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-05-012210526610.3390/ijms22105266Nanomaterial Shape Influence on Cell BehaviorDaniil V. Kladko0Aleksandra S. Falchevskaya1Nikita S. Serov2Artur Y. Prilepskii3International Institute “Solution Chemistry of Advanced Materials and Technologies”, ITMO University, 191002 Saint Petersburg, RussiaInternational Institute “Solution Chemistry of Advanced Materials and Technologies”, ITMO University, 191002 Saint Petersburg, RussiaInternational Institute “Solution Chemistry of Advanced Materials and Technologies”, ITMO University, 191002 Saint Petersburg, RussiaInternational Institute “Solution Chemistry of Advanced Materials and Technologies”, ITMO University, 191002 Saint Petersburg, RussiaNanomaterials are proven to affect the biological activity of mammalian and microbial cells profoundly. Despite this fact, only surface chemistry, charge, and area are often linked to these phenomena. Moreover, most attention in this field is directed exclusively at nanomaterial cytotoxicity. At the same time, there is a large body of studies showing the influence of nanomaterials on cellular metabolism, proliferation, differentiation, reprogramming, gene transfer, and many other processes. Furthermore, it has been revealed that in all these cases, the shape of the nanomaterial plays a crucial role. In this paper, the mechanisms of nanomaterials shape control, approaches toward its synthesis, and the influence of nanomaterial shape on various biological activities of mammalian and microbial cells, such as proliferation, differentiation, and metabolism, as well as the prospects of this emerging field, are reviewed.https://www.mdpi.com/1422-0067/22/10/5266nanoparticleshapemicrobial cellmammalian cellcrystal growthanisotropic |
| spellingShingle | Daniil V. Kladko Aleksandra S. Falchevskaya Nikita S. Serov Artur Y. Prilepskii Nanomaterial Shape Influence on Cell Behavior International Journal of Molecular Sciences nanoparticle shape microbial cell mammalian cell crystal growth anisotropic |
| title | Nanomaterial Shape Influence on Cell Behavior |
| title_full | Nanomaterial Shape Influence on Cell Behavior |
| title_fullStr | Nanomaterial Shape Influence on Cell Behavior |
| title_full_unstemmed | Nanomaterial Shape Influence on Cell Behavior |
| title_short | Nanomaterial Shape Influence on Cell Behavior |
| title_sort | nanomaterial shape influence on cell behavior |
| topic | nanoparticle shape microbial cell mammalian cell crystal growth anisotropic |
| url | https://www.mdpi.com/1422-0067/22/10/5266 |
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