Inhibiting the Progression of Arterial Calcification with Vitamin K in HemoDialysis Patients (iPACK-HD) Trial: Rationale and Study Design for a Randomized Trial of Vitamin K in Patients with End Stage Kidney Disease

Inhibiting the Progression of Arterial Calcification with Vitamin K in HemoDialysis Patients (iPACK-HD) Trial: Rationale and Study Design for a Randomized Trial of Vitamin K in Patients with End Stage Kidney Disease

Background: Cardiovascular disease, which is due in part to progressive vascular calcification, is the leading cause of death among patients with end stage kidney disease (ESKD) on dialysis. A role for vitamin K in the prevention of vascular calcification is plausible based on the presence of vitami...

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Main Authors: Rachel M Holden, Sarah L Booth, Andrew G Day, Catherine M Clase, Deborah Zimmerman, Louise Moist, M Kyla Shea, Kristin M McCabe, Sophie A Jamal, Sheldon Tobe, Jordan Weinstein, Rao Madhumathi, Michael A Adams, Daren K Heyland
Format: Article
Language:English
Published: SAGE Publishing 2015-05-01
Series:Canadian Journal of Kidney Health and Disease
Online Access:https://doi.org/10.1186/s40697-015-0053-x

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