Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in Canada
Increasing resistance of Eimeria species to anticoccidial medications is an issue in the broiler chicken industry. Using drug-sensitive strains in live-coccidiosis vaccines has been shown to improve anticoccidial effectiveness in US-based broiler production. In Canada, litter is removed between floc...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-02-01
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| Series: | Poultry Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579120307951 |
| _version_ | 1818920189252599808 |
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| author | R.P. Snyder M.T. Guerin B.M. Hargis P.S. Kruth G. Page E. Rejman J.L. Rotolo W. Sears E.G. Zeldenrust J. Whale J.R. Barta |
| author_facet | R.P. Snyder M.T. Guerin B.M. Hargis P.S. Kruth G. Page E. Rejman J.L. Rotolo W. Sears E.G. Zeldenrust J. Whale J.R. Barta |
| author_sort | R.P. Snyder |
| collection | DOAJ |
| description | Increasing resistance of Eimeria species to anticoccidial medications is an issue in the broiler chicken industry. Using drug-sensitive strains in live-coccidiosis vaccines has been shown to improve anticoccidial effectiveness in US-based broiler production. In Canada, litter is removed between flocks, which differ from the US industry practice. Thus, we investigated the use of drug-sensitive vaccine strains in a Canadian broiler production facility with suspected anticoccidial resistance. Weekly fecal samples were collected from flocks before, during, and after vaccine seeding to determine oocyst shedding patterns; following the vaccine seeding, OPG counts from similar aged birds were lower than flocks before live-coccidiosis vaccine use. Eimeria species isolates, collected before and after vaccine seeding, were used in 2 anticoccidial sensitivity tests to evaluate their susceptibility to commercially available anticoccidial medications; a low-dose challenge to define parasite replication, and a high-dose challenge to monitor broiler performance. In both experiments, isolates collected after seeding were more susceptible to almost every anticoccidial medication evaluated compared with the isolates collected before seeding. These results demonstrate an improvement in sensitivity to many anticoccidials after the use of live-coccidiosis vaccines at this facility. However, the regulated removal of litter at the end of each flock required under Canadian broiler chicken production management rules could limit the establishment of vaccine-strain Eimeria species in broiler facilities and could shorten the longevity of improved drug sensitivity observed in this study. |
| first_indexed | 2024-12-20T01:17:48Z |
| format | Article |
| id | doaj.art-314017d69962453aab1584d62dc68e57 |
| institution | Directory Open Access Journal |
| issn | 0032-5791 |
| language | English |
| last_indexed | 2024-12-20T01:17:48Z |
| publishDate | 2021-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Poultry Science |
| spelling | doaj.art-314017d69962453aab1584d62dc68e572022-12-21T19:58:32ZengElsevierPoultry Science0032-57912021-02-011002663674Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in CanadaR.P. Snyder0M.T. Guerin1B.M. Hargis2P.S. Kruth3G. Page4E. Rejman5J.L. Rotolo6W. Sears7E.G. Zeldenrust8J. Whale9J.R. Barta10Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada; Corresponding author:Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, CanadaDivision of Agriculture, Department of Poultry Science, University of Arkansas, Fayetteville 72703, USADepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, CanadaResearch and Development, Trouw Nutrition, Amersfoort 3800 AG, The NetherlandsDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, CanadaDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, CanadaDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, CanadaDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, CanadaDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, CanadaDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, CanadaIncreasing resistance of Eimeria species to anticoccidial medications is an issue in the broiler chicken industry. Using drug-sensitive strains in live-coccidiosis vaccines has been shown to improve anticoccidial effectiveness in US-based broiler production. In Canada, litter is removed between flocks, which differ from the US industry practice. Thus, we investigated the use of drug-sensitive vaccine strains in a Canadian broiler production facility with suspected anticoccidial resistance. Weekly fecal samples were collected from flocks before, during, and after vaccine seeding to determine oocyst shedding patterns; following the vaccine seeding, OPG counts from similar aged birds were lower than flocks before live-coccidiosis vaccine use. Eimeria species isolates, collected before and after vaccine seeding, were used in 2 anticoccidial sensitivity tests to evaluate their susceptibility to commercially available anticoccidial medications; a low-dose challenge to define parasite replication, and a high-dose challenge to monitor broiler performance. In both experiments, isolates collected after seeding were more susceptible to almost every anticoccidial medication evaluated compared with the isolates collected before seeding. These results demonstrate an improvement in sensitivity to many anticoccidials after the use of live-coccidiosis vaccines at this facility. However, the regulated removal of litter at the end of each flock required under Canadian broiler chicken production management rules could limit the establishment of vaccine-strain Eimeria species in broiler facilities and could shorten the longevity of improved drug sensitivity observed in this study.http://www.sciencedirect.com/science/article/pii/S0032579120307951coccidiosisbroiler chickenanticoccidial resistanceanticoccidial sensitivity testcommercial production |
| spellingShingle | R.P. Snyder M.T. Guerin B.M. Hargis P.S. Kruth G. Page E. Rejman J.L. Rotolo W. Sears E.G. Zeldenrust J. Whale J.R. Barta Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in Canada Poultry Science coccidiosis broiler chicken anticoccidial resistance anticoccidial sensitivity test commercial production |
| title | Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in Canada |
| title_full | Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in Canada |
| title_fullStr | Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in Canada |
| title_full_unstemmed | Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in Canada |
| title_short | Restoration of anticoccidial sensitivity to a commercial broiler chicken facility in Canada |
| title_sort | restoration of anticoccidial sensitivity to a commercial broiler chicken facility in canada |
| topic | coccidiosis broiler chicken anticoccidial resistance anticoccidial sensitivity test commercial production |
| url | http://www.sciencedirect.com/science/article/pii/S0032579120307951 |
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