Towards the Development of Long Circulating Phosphatidylserine (PS)- and Phosphatidylglycerol (PG)-Enriched Anti-Inflammatory Liposomes: Is PEGylation Effective?

Towards the Development of Long Circulating Phosphatidylserine (PS)- and Phosphatidylglycerol (PG)-Enriched Anti-Inflammatory Liposomes: Is PEGylation Effective?

The anionic phospholipids (PLs) phosphatidylserine (PS) and phosphatidylglycerol (PG) are endogenous phospholipids with anti-inflammatory and immunomodulatory activity. A potential clinical use requires well-defined systems and for several applications, a long circulation time is desirable. Therefor...

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Bibliographic Details
Main Authors: Miriam E. Klein, Max Rieckmann, Daniel Sedding, Gerd Hause, Annette Meister, Karsten Mäder, Henrike Lucas
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
liposomes
phosphatidylserine
phosphatidylglycerol
nano
PEGylation
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4923/13/2/282

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