The Role of G Protein-Coupled Receptors in the Right Ventricle in Pulmonary Hypertension

The Role of G Protein-Coupled Receptors in the Right Ventricle in Pulmonary Hypertension

Pressure overload of the right ventricle (RV) in pulmonary arterial hypertension (PAH) leads to RV remodeling and failure, an important determinant of outcome in patients with PAH. Several G protein-coupled receptors (GPCRs) are differentially regulated in the RV myocardium, contributing to the path...

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Bibliographic Details
Main Authors: Gayathri Viswanathan, Argen Mamazhakypov, Ralph T. Schermuly, Sudarshan Rajagopal
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
right ventricle
G protein-coupled receptor
pulmonary hypertension
remodeling
dysfunction
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00179/full

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