MatchTope: A tool to predict the cross reactivity of peptides complexed with Major Histocompatibility Complex I

MatchTope: A tool to predict the cross reactivity of peptides complexed with Major Histocompatibility Complex I

The therapeutic targeting of the immune system, for example in vaccinology and cancer treatment, is a challenging task and the subject of active research. Several in silico tools used for predicting immunogenicity are based on the analysis of peptide sequences binding to the Major Histocompatibility...

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Bibliographic Details
Main Authors: Marcus Fabiano de Almeida Mendes, Marcelo de Souza Bragatte, Priscila Vianna, Martiela Vaz de Freitas, Ina Pöhner, Stefan Richter, Rebecca C. Wade, Francisco Mauro Salzano, Gustavo Fioravanti Vieira
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
T-cell
T-cell response
immunoinformatic
cross reactivity
cross reactivity prediction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.930590/full

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