Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken design
A closed-vessel microwave-assisted extraction (MAE) of phenolic compounds from the aerial parts of Inula britannica L. using single-factor experiments and the Box-Behnken design with four independent variables (liquid-to-solid ratio, ethanol concentration, extraction time, and temperature) was inve...
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| Format: | Article |
| Language: | English |
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Society of Chemists and Technologists of Macedonia
2022-06-01
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| Series: | Macedonian Journal of Chemistry and Chemical Engineering |
| Subjects: | |
| Online Access: | https://mjcce.org.mk/index.php/MJCCE/article/view/2483 |
| _version_ | 1818548362111090688 |
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| author | Viktoria Ivanova Antoaneta Trendafilova |
| author_facet | Viktoria Ivanova Antoaneta Trendafilova |
| author_sort | Viktoria Ivanova |
| collection | DOAJ |
| description |
A closed-vessel microwave-assisted extraction (MAE) of phenolic compounds from the aerial parts of Inula britannica L. using single-factor experiments and the Box-Behnken design with four independent variables (liquid-to-solid ratio, ethanol concentration, extraction time, and temperature) was investigated. The ANOVA results showed that the obtained model was significant at a 95 % confidence level. The extraction parameters for the maximal total phenolic content (46.19 mg GAE/g DM) were determined to be 15.13 ml/g liquid-to-solid ratio, 55.95 % EtOH, 73.74 ºC, and 5.73 min. Compared with classical maceration, the proposed MAE of phenolic compounds from I. britannica saves a lot of time and gives a high extraction yield.
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| first_indexed | 2024-12-12T08:18:55Z |
| format | Article |
| id | doaj.art-3145f77c03c24158be8f8f2d7b14261e |
| institution | Directory Open Access Journal |
| issn | 1857-5552 1857-5625 |
| language | English |
| last_indexed | 2024-12-12T08:18:55Z |
| publishDate | 2022-06-01 |
| publisher | Society of Chemists and Technologists of Macedonia |
| record_format | Article |
| series | Macedonian Journal of Chemistry and Chemical Engineering |
| spelling | doaj.art-3145f77c03c24158be8f8f2d7b14261e2022-12-22T00:31:28ZengSociety of Chemists and Technologists of MacedoniaMacedonian Journal of Chemistry and Chemical Engineering1857-55521857-56252022-06-0141110.20450/mjcce.2022.2483Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken designViktoria IvanovaAntoaneta Trendafilova0Laboratory "Chemistry of Natural Products", Institute of Organic Chemistry with Centre of Phytochemistry, Sofia A closed-vessel microwave-assisted extraction (MAE) of phenolic compounds from the aerial parts of Inula britannica L. using single-factor experiments and the Box-Behnken design with four independent variables (liquid-to-solid ratio, ethanol concentration, extraction time, and temperature) was investigated. The ANOVA results showed that the obtained model was significant at a 95 % confidence level. The extraction parameters for the maximal total phenolic content (46.19 mg GAE/g DM) were determined to be 15.13 ml/g liquid-to-solid ratio, 55.95 % EtOH, 73.74 ºC, and 5.73 min. Compared with classical maceration, the proposed MAE of phenolic compounds from I. britannica saves a lot of time and gives a high extraction yield. https://mjcce.org.mk/index.php/MJCCE/article/view/2483Inula britannica L.phenolic compoundsmicrowave-assisted extractionBox- Behnken design |
| spellingShingle | Viktoria Ivanova Antoaneta Trendafilova Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken design Macedonian Journal of Chemistry and Chemical Engineering Inula britannica L. phenolic compounds microwave-assisted extraction Box- Behnken design |
| title | Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken design |
| title_full | Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken design |
| title_fullStr | Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken design |
| title_full_unstemmed | Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken design |
| title_short | Optimization of microwave-assisted extraction of phenolic compounds from Inula britannica L. using the Box-Behnken design |
| title_sort | optimization of microwave assisted extraction of phenolic compounds from inula britannica l using the box behnken design |
| topic | Inula britannica L. phenolic compounds microwave-assisted extraction Box- Behnken design |
| url | https://mjcce.org.mk/index.php/MJCCE/article/view/2483 |
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