DNA methylation alterations across time and space in paediatric brain tumours

DNA methylation alterations across time and space in paediatric brain tumours

Abstract DNA methylation is increasingly used for tumour classification and has expanded upon the > 100 currently known brain tumour entities. A correct diagnosis is the basis for suitable treatment for patients with brain tumours, which is the leading cause of cancer-related death in children. D...

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Bibliographic Details
Main Authors: Anna Wenger, Sandra Ferreyra Vega, Elizabeth Schepke, Maja Löfgren, Thomas Olsson Bontell, Magnus Tisell, Daniel Nilsson, Teresia Kling, Helena Carén
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Acta Neuropathologica Communications
Subjects:
Childhood cancer
DNA methylation
Brain tumour
EPIC methylation array
Heterogeneity
Intratumour
Online Access:https://doi.org/10.1186/s40478-022-01406-8

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