Preliminary Study on the Efficacy of a Recombinant, Subunit SARS-CoV-2 Animal Vaccine against Virulent SARS-CoV-2 Challenge in Cats

Preliminary Study on the Efficacy of a Recombinant, Subunit SARS-CoV-2 Animal Vaccine against Virulent SARS-CoV-2 Challenge in Cats

The objective of this work was to evaluate the safety and efficacy of a recombinant, subunit SARS-CoV-2 animal vaccine in cats against virulent SARS-CoV-2 challenge. Two groups of cats were immunized with two doses of either a recombinant SARS-CoV-2 spike protein vaccine or a placebo, administered t...

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Bibliographic Details
Main Authors: Igor Morozov, Natasha N. Gaudreault, Jessie D. Trujillo, Sabarish V. Indran, Konner Cool, Taeyong Kwon, David A. Meekins, Velmurugan Balaraman, Bianca Libanori Artiaga, Daniel W. Madden, Chester McDowell, Bradley Njaa, Jamie Retallick, Nicole Hainer, Jason Millership, William C. Wilson, George Tkalcevic, Hanne Vander Horst, Yulia Burakova, Vickie King, Kendra Hutchinson, John M. Hardham, Denise J. Schwahn, Mahesh Kumar, Juergen A. Richt
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Vaccines
Subjects:
SARS-CoV-2
cats
feline
recombinant vaccine
virus-neutralizing antibodies
immune response
Online Access:https://www.mdpi.com/2076-393X/11/12/1831

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