Immune microenvironment and intrinsic subtyping in hormone receptor-positive/HER2-negative breast cancer

Abstract Little is known regarding the interaction between immune microenvironment and tumor biology in hormone receptor (HR)+/HER2− breast cancer (BC). We here assess pretreatment gene-expression data from 66 HR+/HER2− early BCs from the LETLOB trial and show that non-luminal tumors (HER2-enriched,...

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Bibliographic Details
Main Authors: Gaia Griguolo, Maria Vittoria Dieci, Laia Paré, Federica Miglietta, Daniele Giulio Generali, Antonio Frassoldati, Luigi Cavanna, Giancarlo Bisagni, Federico Piacentini, Enrico Tagliafico, Katia Cagossi, Guido Ficarra, Aleix Prat, Pierfranco Conte, Valentina Guarneri
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00223-x