Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation
BackgroundTranscatheter annuloplasty is meant to target annular dilatation and is therefore mainly applied in functional tricuspid regurgitation (TR). Due to recent recognition of varying disease pathophysiology and differentiation of ventricular and atrial functional TR (VFTR and AFTR), comparative...
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1189920/full |
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| author | Fabian Barbieri Isabel Mattig Isabel Mattig Isabel Mattig Niklas Beyhoff Niklas Beyhoff Tharusan Thevathasan Tharusan Thevathasan Tharusan Thevathasan Elena Romero Dorta Carsten Skurk Carsten Skurk Karl Stangl Karl Stangl Ulf Landmesser Ulf Landmesser Ulf Landmesser Mario Kasner Henryk Dreger Henryk Dreger Markus Reinthaler Markus Reinthaler |
| author_facet | Fabian Barbieri Isabel Mattig Isabel Mattig Isabel Mattig Niklas Beyhoff Niklas Beyhoff Tharusan Thevathasan Tharusan Thevathasan Tharusan Thevathasan Elena Romero Dorta Carsten Skurk Carsten Skurk Karl Stangl Karl Stangl Ulf Landmesser Ulf Landmesser Ulf Landmesser Mario Kasner Henryk Dreger Henryk Dreger Markus Reinthaler Markus Reinthaler |
| author_sort | Fabian Barbieri |
| collection | DOAJ |
| description | BackgroundTranscatheter annuloplasty is meant to target annular dilatation and is therefore mainly applied in functional tricuspid regurgitation (TR). Due to recent recognition of varying disease pathophysiology and differentiation of ventricular and atrial functional TR (VFTR and AFTR), comparative data regarding procedural success for both disease entities are required.MethodsIn this consecutively enrolled observational cohort study, 65 patients undergoing transcatheter annuloplasty with a Cardioband® device were divided into VFTR (n = 35, 53.8%) and AFTR (n = 30, 46.2%). Procedural success was assessed by comparing changes in annulus dilatation, vena contracta (VC) width, effective regurgitation orifice area (EROA), as well as reduction in TR severity.ResultsOverall, improvement of TR by at least two grades was achieved in 59 patients (90.8%), and improvement of TR by at least three grades was realised in 32 patients (49.2%). Residual TR of ≤2 was observed in 52 patients (80.0%). No significant differences in annulus diameter reduction [VFTR: 11 mm (9–13) vs. AFTR: 12 mm (9–16), p = 0.210], VC reduction [12 mm (8–14) vs. 12 mm (7–14), p = 0.868], and EROA reduction [0.62 cm2 (0.45–1.10) vs. 0.54 cm2 (0.40–0.70), p = 0.204] were reported. Improvement by at least two grades [27 (90.0%) vs. 32 (91.4%), p = 1.0] and three grades [14 (46.7%) vs. 18 (51.4%), p = 0.805] was similar in VFTR and AFTR, respectively. No significant difference in the accomplishment of TR grade of ≤2 [21 (70.0%) vs. 31 (88.6%), p = 0.118] was noted.ConclusionAccording to our results from a real-world scenario, transcatheter annuloplasty with the Cardioband® device may be applied in both VFTR and AFTR with evidence of significant procedural TR reduction. |
| first_indexed | 2024-03-12T16:59:31Z |
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| id | doaj.art-315611b75b66436bb148f22c09b7c1f3 |
| institution | Directory Open Access Journal |
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| language | English |
| last_indexed | 2024-03-12T16:59:31Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-315611b75b66436bb148f22c09b7c1f32023-08-07T15:07:46ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-08-011010.3389/fcvm.2023.11899201189920Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitationFabian Barbieri0Isabel Mattig1Isabel Mattig2Isabel Mattig3Niklas Beyhoff4Niklas Beyhoff5Tharusan Thevathasan6Tharusan Thevathasan7Tharusan Thevathasan8Elena Romero Dorta9Carsten Skurk10Carsten Skurk11Karl Stangl12Karl Stangl13Ulf Landmesser14Ulf Landmesser15Ulf Landmesser16Mario Kasner17Henryk Dreger18Henryk Dreger19Markus Reinthaler20Markus Reinthaler21Deutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, GermanyBerlin Institute of Health at Charité—Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyBerlin Institute of Health at Charité—Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyBerlin Institute of Health at Charité—Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Berlin, GermanyInstitute of Medical Informatics, Charité—Universitätsmedizin Berlin, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyBerlin Institute of Health at Charité—Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, GermanyBerlin Institute of Health at Charité—Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyDZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, GermanyDeutsches Herzzentrum der Charité, Department of Cardiology, Angiology and Intensive Care Medicine, Berlin, GermanyInstitute of Active Polymers and Berlin-Brandenburg Center for Regenerative Therapies, Helmholtz-Zentrum Hereon, Teltow, GermanyBackgroundTranscatheter annuloplasty is meant to target annular dilatation and is therefore mainly applied in functional tricuspid regurgitation (TR). Due to recent recognition of varying disease pathophysiology and differentiation of ventricular and atrial functional TR (VFTR and AFTR), comparative data regarding procedural success for both disease entities are required.MethodsIn this consecutively enrolled observational cohort study, 65 patients undergoing transcatheter annuloplasty with a Cardioband® device were divided into VFTR (n = 35, 53.8%) and AFTR (n = 30, 46.2%). Procedural success was assessed by comparing changes in annulus dilatation, vena contracta (VC) width, effective regurgitation orifice area (EROA), as well as reduction in TR severity.ResultsOverall, improvement of TR by at least two grades was achieved in 59 patients (90.8%), and improvement of TR by at least three grades was realised in 32 patients (49.2%). Residual TR of ≤2 was observed in 52 patients (80.0%). No significant differences in annulus diameter reduction [VFTR: 11 mm (9–13) vs. AFTR: 12 mm (9–16), p = 0.210], VC reduction [12 mm (8–14) vs. 12 mm (7–14), p = 0.868], and EROA reduction [0.62 cm2 (0.45–1.10) vs. 0.54 cm2 (0.40–0.70), p = 0.204] were reported. Improvement by at least two grades [27 (90.0%) vs. 32 (91.4%), p = 1.0] and three grades [14 (46.7%) vs. 18 (51.4%), p = 0.805] was similar in VFTR and AFTR, respectively. No significant difference in the accomplishment of TR grade of ≤2 [21 (70.0%) vs. 31 (88.6%), p = 0.118] was noted.ConclusionAccording to our results from a real-world scenario, transcatheter annuloplasty with the Cardioband® device may be applied in both VFTR and AFTR with evidence of significant procedural TR reduction.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1189920/fullatrial functional tricuspid regurgitationventricular functional tricuspid regurgitationtranscatheter annuloplastyCardioband®interventional echocardiography |
| spellingShingle | Fabian Barbieri Isabel Mattig Isabel Mattig Isabel Mattig Niklas Beyhoff Niklas Beyhoff Tharusan Thevathasan Tharusan Thevathasan Tharusan Thevathasan Elena Romero Dorta Carsten Skurk Carsten Skurk Karl Stangl Karl Stangl Ulf Landmesser Ulf Landmesser Ulf Landmesser Mario Kasner Henryk Dreger Henryk Dreger Markus Reinthaler Markus Reinthaler Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation Frontiers in Cardiovascular Medicine atrial functional tricuspid regurgitation ventricular functional tricuspid regurgitation transcatheter annuloplasty Cardioband® interventional echocardiography |
| title | Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation |
| title_full | Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation |
| title_fullStr | Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation |
| title_full_unstemmed | Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation |
| title_short | Procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation |
| title_sort | procedural success of transcatheter annuloplasty in ventricular and atrial functional tricuspid regurgitation |
| topic | atrial functional tricuspid regurgitation ventricular functional tricuspid regurgitation transcatheter annuloplasty Cardioband® interventional echocardiography |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1189920/full |
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