Total Flavonoids Extracts of <i>Apocynum</i> L. from the Ili River Valley Region at Different Harvesting Periods and Bioactivity Analysis
In the current study, the total content from two <i>Apocynum</i> species leaves (<i>Apocynum venetum</i> and <i>Apocynum hendersonii</i>) collected from the Ili River Valley Region were extracted, and their bioactivities were investigated. The results showed a sig...
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MDPI AG
2022-10-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/21/7343 |
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| author | Deyi Shao Gang Gao Aminu Shehu Abubakar Hanipa Hazaisi Ping Chen Jikang Chen Kunmei Chen Xiaofei Wang Yue Wang Yu Chen Chunming Yu Aiguo Zhu |
| author_facet | Deyi Shao Gang Gao Aminu Shehu Abubakar Hanipa Hazaisi Ping Chen Jikang Chen Kunmei Chen Xiaofei Wang Yue Wang Yu Chen Chunming Yu Aiguo Zhu |
| author_sort | Deyi Shao |
| collection | DOAJ |
| description | In the current study, the total content from two <i>Apocynum</i> species leaves (<i>Apocynum venetum</i> and <i>Apocynum hendersonii</i>) collected from the Ili River Valley Region were extracted, and their bioactivities were investigated. The results showed a significant variation in the total flavonoid contents in the leaf samples collected at different periods (June, July, August, and September), with the highest content in August (60.11 ± 0.38 mg RE/g DW for <i>A. venetum</i> and 56.56 ± 0.24 mg RE/g DW for <i>A. hendersonii</i>), and the lowest in June (22.36 ± 0.05 mg RE/g DW for <i>A. venetum</i> and 20.79 ± 0.02 mg RE/g DW for <i>A. hendersonii</i>). The total flavonoid content was comparably higher in <i>A. venetum</i> than in <i>A. hendersonii</i>. Leaves extracts from the two species demonstrated strong bioactivity, which positively correlated with the total flavonoid contents. The anti-oxidative activity of <i>A. venetum</i> was higher than that of <i>A. hendersonii</i> in tandem with its higher flavonoid contents; the antibacterial activity, however, was conversely opposite. Furthermore, a total of 83 flavonoid metabolites were identified in the two species based on UPLC-ESI-MS/MS, out of which 24 metabolites were differentially accumulated. The variability in these metabolites might be the reason for the different bioactivities displayed by the two species. The present study provides insight into the optimal harvest time for <i>Apocynum</i> species planted in the major distribution area of the Ili River Valley and the specific utilization of <i>A. venetum</i> and <i>A. hendersonii</i>. |
| first_indexed | 2024-03-09T18:47:46Z |
| format | Article |
| id | doaj.art-3156b3d98c424c7faa5343ef8e608a95 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T18:47:46Z |
| publishDate | 2022-10-01 |
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| record_format | Article |
| series | Molecules |
| spelling | doaj.art-3156b3d98c424c7faa5343ef8e608a952023-11-24T06:02:39ZengMDPI AGMolecules1420-30492022-10-012721734310.3390/molecules27217343Total Flavonoids Extracts of <i>Apocynum</i> L. from the Ili River Valley Region at Different Harvesting Periods and Bioactivity AnalysisDeyi Shao0Gang Gao1Aminu Shehu Abubakar2Hanipa Hazaisi3Ping Chen4Jikang Chen5Kunmei Chen6Xiaofei Wang7Yue Wang8Yu Chen9Chunming Yu10Aiguo Zhu11Institute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaIli Agricultural Science Institute, Yining 835100, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaInstitute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, ChinaIn the current study, the total content from two <i>Apocynum</i> species leaves (<i>Apocynum venetum</i> and <i>Apocynum hendersonii</i>) collected from the Ili River Valley Region were extracted, and their bioactivities were investigated. The results showed a significant variation in the total flavonoid contents in the leaf samples collected at different periods (June, July, August, and September), with the highest content in August (60.11 ± 0.38 mg RE/g DW for <i>A. venetum</i> and 56.56 ± 0.24 mg RE/g DW for <i>A. hendersonii</i>), and the lowest in June (22.36 ± 0.05 mg RE/g DW for <i>A. venetum</i> and 20.79 ± 0.02 mg RE/g DW for <i>A. hendersonii</i>). The total flavonoid content was comparably higher in <i>A. venetum</i> than in <i>A. hendersonii</i>. Leaves extracts from the two species demonstrated strong bioactivity, which positively correlated with the total flavonoid contents. The anti-oxidative activity of <i>A. venetum</i> was higher than that of <i>A. hendersonii</i> in tandem with its higher flavonoid contents; the antibacterial activity, however, was conversely opposite. Furthermore, a total of 83 flavonoid metabolites were identified in the two species based on UPLC-ESI-MS/MS, out of which 24 metabolites were differentially accumulated. The variability in these metabolites might be the reason for the different bioactivities displayed by the two species. The present study provides insight into the optimal harvest time for <i>Apocynum</i> species planted in the major distribution area of the Ili River Valley and the specific utilization of <i>A. venetum</i> and <i>A. hendersonii</i>.https://www.mdpi.com/1420-3049/27/21/7343<i>Apocynum venetum</i><i>Apocynum hendersonii</i>antioxidantantimicrobialflavonoidsmetabolomics |
| spellingShingle | Deyi Shao Gang Gao Aminu Shehu Abubakar Hanipa Hazaisi Ping Chen Jikang Chen Kunmei Chen Xiaofei Wang Yue Wang Yu Chen Chunming Yu Aiguo Zhu Total Flavonoids Extracts of <i>Apocynum</i> L. from the Ili River Valley Region at Different Harvesting Periods and Bioactivity Analysis Molecules <i>Apocynum venetum</i> <i>Apocynum hendersonii</i> antioxidant antimicrobial flavonoids metabolomics |
| title | Total Flavonoids Extracts of <i>Apocynum</i> L. from the Ili River Valley Region at Different Harvesting Periods and Bioactivity Analysis |
| title_full | Total Flavonoids Extracts of <i>Apocynum</i> L. from the Ili River Valley Region at Different Harvesting Periods and Bioactivity Analysis |
| title_fullStr | Total Flavonoids Extracts of <i>Apocynum</i> L. from the Ili River Valley Region at Different Harvesting Periods and Bioactivity Analysis |
| title_full_unstemmed | Total Flavonoids Extracts of <i>Apocynum</i> L. from the Ili River Valley Region at Different Harvesting Periods and Bioactivity Analysis |
| title_short | Total Flavonoids Extracts of <i>Apocynum</i> L. from the Ili River Valley Region at Different Harvesting Periods and Bioactivity Analysis |
| title_sort | total flavonoids extracts of i apocynum i l from the ili river valley region at different harvesting periods and bioactivity analysis |
| topic | <i>Apocynum venetum</i> <i>Apocynum hendersonii</i> antioxidant antimicrobial flavonoids metabolomics |
| url | https://www.mdpi.com/1420-3049/27/21/7343 |
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