The relationship between phase angle measurements and cardiovascular risk factor in adults: Insights from an epidemiologic cohort study
Summary: Background: This study investigated the practicality of Phase Angle (PhA) as a cellular integrity indicator obtained from bioelectrical impedance and its feasible association with the cardiovascular risk factors among healthy Iranian adults. Methods: This cross-sectional study consisted of...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-10-01
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| Series: | Clinical Nutrition Open Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667268523000347 |
| _version_ | 1827793675131813888 |
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| author | Sara Raji Leila Sadat Bahrami Seyyed Mostafa Arabi Elahe Ebrahimi Miandehi Seyyed Reza Sobhani Zahra Ataee Fatemeh Roudi Saeid Eslami Sahar Sobhani |
| author_facet | Sara Raji Leila Sadat Bahrami Seyyed Mostafa Arabi Elahe Ebrahimi Miandehi Seyyed Reza Sobhani Zahra Ataee Fatemeh Roudi Saeid Eslami Sahar Sobhani |
| author_sort | Sara Raji |
| collection | DOAJ |
| description | Summary: Background: This study investigated the practicality of Phase Angle (PhA) as a cellular integrity indicator obtained from bioelectrical impedance and its feasible association with the cardiovascular risk factors among healthy Iranian adults. Methods: This cross-sectional study consisted of 5000 participants. All biologic impedance and laboratory data were obtained at the time of registration according to the study protocol. Framingham's risk score has been calculated for each participant to assess the risk of cardiovascular disease. Simple and Multiple linear regression analyses were used to determine the relationship between PhA and cardiovascular risk score. Results: The mean age of participants was 45.11+9.97 years, 2294(46%) were males and 2706(54%) were females. Triglyceride, total cholesterol, diastolic blood pressure, Waist hip ratio in women, and Fat mass and Waist Circumference in men were not significant association with Phase angle (P> 0.05). In the multivariable linear regression, high levels of TG, FBS, FFM, and elevated age and BMI were associated directly with high cardiovascular risk scores (P < 0.0001) also, the levels of PhA and HDL were associated negatively with Framingham risk score in both genders (P < 0.05 for all). Conclusions: According to the present study results, Increased cardiovascular risk factor was associated with higher BMI, aging, FM, WHR, TC, LDL, TG, and FBS in both genders, also Phase angle measurements could be a good predictor of cardiovascular disease in both gender men and women. |
| first_indexed | 2024-03-11T18:21:53Z |
| format | Article |
| id | doaj.art-3156d443ecff4215b0008249a596c8f2 |
| institution | Directory Open Access Journal |
| issn | 2667-2685 |
| language | English |
| last_indexed | 2024-03-11T18:21:53Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Nutrition Open Science |
| spelling | doaj.art-3156d443ecff4215b0008249a596c8f22023-10-15T04:38:24ZengElsevierClinical Nutrition Open Science2667-26852023-10-01512634The relationship between phase angle measurements and cardiovascular risk factor in adults: Insights from an epidemiologic cohort studySara Raji0Leila Sadat Bahrami1Seyyed Mostafa Arabi2Elahe Ebrahimi Miandehi3Seyyed Reza Sobhani4Zahra Ataee5Fatemeh Roudi6Saeid Eslami7Sahar Sobhani8Persian Cohort Research Center, Mashhad University of Medical Sciences, Mashhad, IranMetabolic Syndrome Research Center, Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranMetabolic Syndrome Research Center, Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Basic Sciences, School of Medicine, Neyshabur University of Medical Sciences, Neyshabur, IranPersian Cohort Research Center, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Medical Informatics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranPersian Cohort Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Corresponding author. Persian Cohort Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Tel.: +98 9158242665.Summary: Background: This study investigated the practicality of Phase Angle (PhA) as a cellular integrity indicator obtained from bioelectrical impedance and its feasible association with the cardiovascular risk factors among healthy Iranian adults. Methods: This cross-sectional study consisted of 5000 participants. All biologic impedance and laboratory data were obtained at the time of registration according to the study protocol. Framingham's risk score has been calculated for each participant to assess the risk of cardiovascular disease. Simple and Multiple linear regression analyses were used to determine the relationship between PhA and cardiovascular risk score. Results: The mean age of participants was 45.11+9.97 years, 2294(46%) were males and 2706(54%) were females. Triglyceride, total cholesterol, diastolic blood pressure, Waist hip ratio in women, and Fat mass and Waist Circumference in men were not significant association with Phase angle (P> 0.05). In the multivariable linear regression, high levels of TG, FBS, FFM, and elevated age and BMI were associated directly with high cardiovascular risk scores (P < 0.0001) also, the levels of PhA and HDL were associated negatively with Framingham risk score in both genders (P < 0.05 for all). Conclusions: According to the present study results, Increased cardiovascular risk factor was associated with higher BMI, aging, FM, WHR, TC, LDL, TG, and FBS in both genders, also Phase angle measurements could be a good predictor of cardiovascular disease in both gender men and women.http://www.sciencedirect.com/science/article/pii/S2667268523000347Biological impedancePhase angleCardiovascular |
| spellingShingle | Sara Raji Leila Sadat Bahrami Seyyed Mostafa Arabi Elahe Ebrahimi Miandehi Seyyed Reza Sobhani Zahra Ataee Fatemeh Roudi Saeid Eslami Sahar Sobhani The relationship between phase angle measurements and cardiovascular risk factor in adults: Insights from an epidemiologic cohort study Clinical Nutrition Open Science Biological impedance Phase angle Cardiovascular |
| title | The relationship between phase angle measurements and cardiovascular risk factor in adults: Insights from an epidemiologic cohort study |
| title_full | The relationship between phase angle measurements and cardiovascular risk factor in adults: Insights from an epidemiologic cohort study |
| title_fullStr | The relationship between phase angle measurements and cardiovascular risk factor in adults: Insights from an epidemiologic cohort study |
| title_full_unstemmed | The relationship between phase angle measurements and cardiovascular risk factor in adults: Insights from an epidemiologic cohort study |
| title_short | The relationship between phase angle measurements and cardiovascular risk factor in adults: Insights from an epidemiologic cohort study |
| title_sort | relationship between phase angle measurements and cardiovascular risk factor in adults insights from an epidemiologic cohort study |
| topic | Biological impedance Phase angle Cardiovascular |
| url | http://www.sciencedirect.com/science/article/pii/S2667268523000347 |
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