Vaccination therapy for inflammatory bowel disease
Recently, several novel medications, such as Ustekinumab, Infliximab, and Vedolizumab, have emerged as potential options for inflammatory bowel disease(IBD) management. Despite achieving some effects in clinical applications, these therapies are still plagued by inadequate response rates and adverse...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-08-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2023.2259418 |
| _version_ | 1827767355053178880 |
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| author | Yafei Liu Fei Liao |
| author_facet | Yafei Liu Fei Liao |
| author_sort | Yafei Liu |
| collection | DOAJ |
| description | Recently, several novel medications, such as Ustekinumab, Infliximab, and Vedolizumab, have emerged as potential options for inflammatory bowel disease(IBD) management. Despite achieving some effects in clinical applications, these therapies are still plagued by inadequate response rates and adverse side effects. With rapid progress in immunological research, therapeutic vaccines are gaining traction as an alternative. These vaccines aim to activate the body’s immune system to generate specific antibodies, thereby offering a potential avenue for treating IBD. The efficacy and safety of vaccines, coupled with their potential to mitigate the financial and healthcare burden associated with disease treatment, render therapeutic vaccines a more favorable approach for managing patients with IBD. In this review, we critically examine the existing literature pertaining to therapeutic vaccines for IBD, aiming to offer researchers a comprehensive understanding of their applications and prospects and stimulate novel vaccine development by presenting innovative ideas in this field. |
| first_indexed | 2024-03-11T11:57:35Z |
| format | Article |
| id | doaj.art-315b88065d21472ab02c80d0c872a453 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T11:57:35Z |
| publishDate | 2023-08-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-315b88065d21472ab02c80d0c872a4532023-11-08T11:55:20ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-08-0119210.1080/21645515.2023.22594182259418Vaccination therapy for inflammatory bowel diseaseYafei Liu0Fei Liao1Renmin Hospital of Wuhan UniversityRenmin Hospital of Wuhan UniversityRecently, several novel medications, such as Ustekinumab, Infliximab, and Vedolizumab, have emerged as potential options for inflammatory bowel disease(IBD) management. Despite achieving some effects in clinical applications, these therapies are still plagued by inadequate response rates and adverse side effects. With rapid progress in immunological research, therapeutic vaccines are gaining traction as an alternative. These vaccines aim to activate the body’s immune system to generate specific antibodies, thereby offering a potential avenue for treating IBD. The efficacy and safety of vaccines, coupled with their potential to mitigate the financial and healthcare burden associated with disease treatment, render therapeutic vaccines a more favorable approach for managing patients with IBD. In this review, we critically examine the existing literature pertaining to therapeutic vaccines for IBD, aiming to offer researchers a comprehensive understanding of their applications and prospects and stimulate novel vaccine development by presenting innovative ideas in this field.http://dx.doi.org/10.1080/21645515.2023.2259418inflammatory bowel diseasevaccination therapyintestinal immunityintestinal microbiotaangiogenesisparasite vaccine |
| spellingShingle | Yafei Liu Fei Liao Vaccination therapy for inflammatory bowel disease Human Vaccines & Immunotherapeutics inflammatory bowel disease vaccination therapy intestinal immunity intestinal microbiota angiogenesis parasite vaccine |
| title | Vaccination therapy for inflammatory bowel disease |
| title_full | Vaccination therapy for inflammatory bowel disease |
| title_fullStr | Vaccination therapy for inflammatory bowel disease |
| title_full_unstemmed | Vaccination therapy for inflammatory bowel disease |
| title_short | Vaccination therapy for inflammatory bowel disease |
| title_sort | vaccination therapy for inflammatory bowel disease |
| topic | inflammatory bowel disease vaccination therapy intestinal immunity intestinal microbiota angiogenesis parasite vaccine |
| url | http://dx.doi.org/10.1080/21645515.2023.2259418 |
| work_keys_str_mv | AT yafeiliu vaccinationtherapyforinflammatoryboweldisease AT feiliao vaccinationtherapyforinflammatoryboweldisease |