Natural Killer Cells Regulate the Maturation of Liver Sinusoidal Endothelial Cells Thereby Promoting Intrahepatic T‐Cell Responses in a Mouse Model

Natural Killer Cells Regulate the Maturation of Liver Sinusoidal Endothelial Cells Thereby Promoting Intrahepatic T‐Cell Responses in a Mouse Model

Functional maturation of liver sinusoidal endothelial cells (LSECs) plays an important role in intrahepatic T‐cell activation and control of viral infections. Natural killer (NK) cells have been reported to prompt the maturation of antigen‐presenting cells (APCs), especially for dendritic cells (DCs...

Full description

Bibliographic Details
Main Authors:	Yanqin Du, Hu Yan, Shi Zou, Tanvi Khera, Jia Li, Meihong Han, Xiaoli Yang, Baoju Wang, Jia Liu, Shuilin Sun, Xin Zheng, Ulf Dittmer, Mengji Lu, Dongliang Yang, Heiner Wedemeyer, Jun Wu
Format:	Article
Language:	English
Published:	Wolters Kluwer Health/LWW 2021-05-01
Series:	Hepatology Communications
Online Access:	https://doi.org/10.1002/hep4.1676

Similar Items

The expression of PD-1 ligands and their involvement in regulation of T cell functions in acute and chronic woodchuck hepatitis virus infection.
by: Ejuan Zhang, et al.
Published: (2011-01-01)

Irreversible impact of chronic hepatitis C virus infection on human natural killer cell diversity
by: Benedikt Strunz, et al.
Published: (2018-07-01)

Cytokine-induced killer cell/dendritic cell combined with cytokine-induced killer cell immunotherapy for treating advanced gastrointestinal cancer
by: Hansong Du, et al.
Published: (2020-04-01)

The Cytotoxic Activity of Natural Killer Cells Is Suppressed by IL-10+ Regulatory T Cells During Acute Retroviral Infection
by: Elisabeth Littwitz-Salomon, et al.
Published: (2018-08-01)

Friend retrovirus infection induces the development of memory-like natural killer cells
by: Elisabeth Littwitz-Salomon, et al.
Published: (2018-10-01)

Hepatitis B Virus-Specific CD8+ T Cells Maintain Functional Exhaustion after Antigen Reexposure in an Acute Activation Immune Environment
by: Qin Wang, et al.
Published: (2018-02-01)

In situ characterization of intrahepatic non-parenchymal cells in PSC reveals phenotypic patterns associated with disease severity.
by: Lena Berglin, et al.
Published: (2014-01-01)

Cytomegalovirus-Driven Adaptive-Like Natural Killer Cell Expansions Are Unaffected by Concurrent Chronic Hepatitis Virus Infections
by: David F. G. Malone, et al.
Published: (2017-05-01)

Naringenin Impedes the Differentiation of Mouse Hematopoietic Stem Cells Derived from Bone Marrow into Mature Dendritic Cells, thereby Prolonging Allograft Survival
by: Puxun Tian, et al.
Published: (2023-05-01)

Transjugular intrahepatic portosystemic shunt for the treatment of hepatic sinusoidal obstruction syndrome caused by pyrrolizidine alkaloids: A multicenter retrospective study
by: Chaoyang Wang, et al.
Published: (2024-01-01)

Chronic hepatitis C virus infection irreversibly impacts human natural killer cell repertoire diversity
by: Benedikt Strunz, et al.
Published: (2018-06-01)

Susceptibility of different hepatitis B virus isolates to interferon-alpha in a mouse model based on hydrodynamic injection.
by: Jingjiao Song, et al.
Published: (2014-01-01)

Cutting edge: activation by innate cytokines or microbial antigens can cause arrest of natural killer T cell patrolling of liver sinusoids.
by: Velázquez, P, et al.
Published: (2008)

Toll-like receptor-mediated innate immunity orchestrates adaptive immune responses in HBV infection
by: Yanqin Du, et al.
Published: (2022-07-01)

Uterine Natural Killer Cells
by: Dorothy K. Sojka, et al.
Published: (2019-05-01)

Characterization of the Treg Response in the Hepatitis B Virus Hydrodynamic Injection Mouse Model.
by: Kirsten K Dietze, et al.
Published: (2016-01-01)

AND THEREBY HANGS A TALE
by: Jeffrey Archer 507936
Published: (2010)

Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses
by: Grammatiki Fotaki, et al.
Published: (2018-03-01)

Denervation alters the secretome of myofibers and thereby affects muscle stem cell lineage progression and functionality
by: Henriette Henze, et al.
Published: (2024-03-01)

IFNγ suppresses the expression of GFI1 and thereby inhibits Th2 cell proliferation.
by: Murshed H Sarkar, et al.
Published: (2021-01-01)

TLR2 Expression in Peripheral CD4+ T Cells Promotes Th17 Response and Is Associated with Disease Aggravation of Hepatitis B Virus-Related Acute-On-Chronic Liver Failure
by: Chunli Xu, et al.
Published: (2017-11-01)

Liver sinusoidal endothelial cells: an antiviral "defendothelium".
by: Klenerman, P, et al.
Published: (2015)

Corrigendum: TLR2 Expression in Peripheral CD4+ T Cells Promotes Th17 Response and Is Associated with Disease Aggravation of Hepatitis B Virus-Related Acute-On-Chronic Liver Failure
by: Chunli Xu, et al.
Published: (2020-07-01)

Transjugular intrahepatic portosystemic shunt for hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum
by: Lijie Zhang, et al.
Published: (2021-01-01)

Controlled Attenuation Parameter Is Associated with a Distinct Systemic Inflammatory Milieu after Clearance of HCV Infection
by: Yanqin Du, et al.
Published: (2023-05-01)

Extracellular Vesicle Transfer from Endothelial Cells Drives VE-Cadherin Expression in Breast Cancer Cells, Thereby Causing Heterotypic Cell Contacts
by: Maryam Rezaei, et al.
Published: (2020-08-01)

Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg loss
by: Shue Xiong, et al.
Published: (2021-07-01)

Naturel Killer Cells
by: Alper TEKELİ, et al.
Published: (1997-06-01)

Natural killer T cells
by: Jean Kanellopoulos
Published: (2015-12-01)

Unlocking Glioblastoma Secrets: Natural Killer Cell Therapy against Cancer Stem Cells
by: Yuanning Du, et al.
Published: (2023-12-01)

Killer cell lectin-like receptors and the natural killer cell gene complex.
by: Nylenna, O, et al.
Published: (2005)

Infections, Reactions of Natural Killer T Cells and Natural Killer Cells, and Kidney Injury
by: Takahiro Uchida, et al.
Published: (2022-01-01)

Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis
by: Yuichi Tsuchiya, et al.
Published: (2023-10-01)

LiCl induces TNF-α and FasL production, thereby stimulating apoptosis in cancer cells
by: Thiele Wilko, et al.
Published: (2011-05-01)

The central role of natural killer cells in preeclampsia
by: Xiaoqi Wei, et al.
Published: (2023-02-01)

Protein-energy malnutrition halts hemopoietic progenitor cells in the G0/G1 cell cycle stage, thereby altering cell production rates
by: P. Borelli, et al.
Published: (2009-06-01)

Correction: Metformin promotes the survival of transplanted cardiosphere-derived cells thereby enhancing their therapeutic effect against myocardial infarction
by: Rongchuan Yue, et al.
Published: (2022-12-01)

Different antiviral effects of IFNα subtypes in a mouse model of HBV infection
by: Jingjiao Song, et al.
Published: (2017-03-01)

Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury
by: Sophia Papaioannou, et al.
Published: (2023-08-01)

Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro
by: March, Sandra, et al.
Published: (2012)