Electrocardiographic Findings and Serum Troponin I in Carbon Monoxide Poisoned Patients
Carbon monoxide (CO) poisoning, though with different sources, is one of the most deadly emergencies in all countries. CO can threaten men's life by several paths especially cardiac complications, which can mimic other cardiac problems such as myocardial infarction. The objective of this study...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2012-03-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/3880 |
| _version_ | 1818758667148722176 |
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| author | Shokoufeh Hajsadeghi Nader Tavakkoli Scott Reza Jafarian Kerman Ali Shahabadi Mojtaba Khojand |
| author_facet | Shokoufeh Hajsadeghi Nader Tavakkoli Scott Reza Jafarian Kerman Ali Shahabadi Mojtaba Khojand |
| author_sort | Shokoufeh Hajsadeghi |
| collection | DOAJ |
| description | Carbon monoxide (CO) poisoning, though with different sources, is one of the most deadly emergencies in all countries. CO can threaten men's life by several paths especially cardiac complications, which can mimic other cardiac problems such as myocardial infarction. The objective of this study was to determine ECG findings and serum troponin I levels in CO poisoned patients. In this analytical cross-sectional study, 63 CO poisoning patients were consecutively included from hospital's emergency departments. CO content was measured by a CO-oximeter and an electrocardiography was taken first thing on admission. Arterial blood gas (ABG), troponin I and other data was collected afterwards. Data were divided by age groups (adults and children) and gender. CO content was significantly higher only in subjects with normal T wave compared to patients with inverted T wave in their initial ECG (P=0.016). No other significant difference was noticed. None of the ABG findings correlated significantly with CO content. Also no significant correlation was found with CO content after stratification by gender and age groups, but pH in children (r=-0.484, P=0.026). CO content was significantly higher in adults (P=0.023), but other ABG data were not significantly different. Only 3 patients had elevated troponin I. Receiver operating characteristic (ROC) analysis showed no significant cutoff points in CO content for ECG changes. No significant specific change in electrocardiograms (ECG) could contribute carboxyhemoglobin content in carbon monoxide poisoned patients. In addition, no specific difference was found between adults and pediatric subjects' ECGs. All other findings seemed to be accidental. |
| first_indexed | 2024-12-18T06:30:28Z |
| format | Article |
| id | doaj.art-315fc1d3278d4c2a9501da9755b06b6b |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-18T06:30:28Z |
| publishDate | 2012-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-315fc1d3278d4c2a9501da9755b06b6b2022-12-21T21:17:55ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942012-03-01503Electrocardiographic Findings and Serum Troponin I in Carbon Monoxide Poisoned PatientsShokoufeh Hajsadeghi0Nader Tavakkoli1Scott Reza Jafarian Kerman2Ali Shahabadi3Mojtaba Khojand4Department of Cardiology, Rasoul-e-Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Emergency Medicine, Rasoul-e-Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran.Students Scientific Research Committee, Tehran University of Medical Sciences, Tehran, Iran.Department of Emergency Medicine, Rasoul-e-Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran.Students Scientific Research Committee, Tehran University of Medical Sciences, Tehran, Iran.Carbon monoxide (CO) poisoning, though with different sources, is one of the most deadly emergencies in all countries. CO can threaten men's life by several paths especially cardiac complications, which can mimic other cardiac problems such as myocardial infarction. The objective of this study was to determine ECG findings and serum troponin I levels in CO poisoned patients. In this analytical cross-sectional study, 63 CO poisoning patients were consecutively included from hospital's emergency departments. CO content was measured by a CO-oximeter and an electrocardiography was taken first thing on admission. Arterial blood gas (ABG), troponin I and other data was collected afterwards. Data were divided by age groups (adults and children) and gender. CO content was significantly higher only in subjects with normal T wave compared to patients with inverted T wave in their initial ECG (P=0.016). No other significant difference was noticed. None of the ABG findings correlated significantly with CO content. Also no significant correlation was found with CO content after stratification by gender and age groups, but pH in children (r=-0.484, P=0.026). CO content was significantly higher in adults (P=0.023), but other ABG data were not significantly different. Only 3 patients had elevated troponin I. Receiver operating characteristic (ROC) analysis showed no significant cutoff points in CO content for ECG changes. No significant specific change in electrocardiograms (ECG) could contribute carboxyhemoglobin content in carbon monoxide poisoned patients. In addition, no specific difference was found between adults and pediatric subjects' ECGs. All other findings seemed to be accidental.https://acta.tums.ac.ir/index.php/acta/article/view/3880Carbon monoxidePoisoningElectrocardiographyTropinin I |
| spellingShingle | Shokoufeh Hajsadeghi Nader Tavakkoli Scott Reza Jafarian Kerman Ali Shahabadi Mojtaba Khojand Electrocardiographic Findings and Serum Troponin I in Carbon Monoxide Poisoned Patients Acta Medica Iranica Carbon monoxide Poisoning Electrocardiography Tropinin I |
| title | Electrocardiographic Findings and Serum Troponin I in Carbon Monoxide Poisoned Patients |
| title_full | Electrocardiographic Findings and Serum Troponin I in Carbon Monoxide Poisoned Patients |
| title_fullStr | Electrocardiographic Findings and Serum Troponin I in Carbon Monoxide Poisoned Patients |
| title_full_unstemmed | Electrocardiographic Findings and Serum Troponin I in Carbon Monoxide Poisoned Patients |
| title_short | Electrocardiographic Findings and Serum Troponin I in Carbon Monoxide Poisoned Patients |
| title_sort | electrocardiographic findings and serum troponin i in carbon monoxide poisoned patients |
| topic | Carbon monoxide Poisoning Electrocardiography Tropinin I |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/3880 |
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