Two Operational Modes of Cardio-Respiratory Coupling Revealed by Pulse-Respiration Quotient
Due to the fact that respiratory breath-to-breath and cardiac intervals between two successive R peaks (<i>BBI</i> and <i>RRI</i>, respectively) are not temporally concurrent, in a previous paper, we proposed a method to calculate both the integer and non-integer parts of the...
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MDPI AG
2023-01-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/10/2/180 |
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| author | Aleksandar Kalauzi Zoran Matić Mirjana M. Platiša Tijana Bojić |
| author_facet | Aleksandar Kalauzi Zoran Matić Mirjana M. Platiša Tijana Bojić |
| author_sort | Aleksandar Kalauzi |
| collection | DOAJ |
| description | Due to the fact that respiratory breath-to-breath and cardiac intervals between two successive R peaks (<i>BBI</i> and <i>RRI</i>, respectively) are not temporally concurrent, in a previous paper, we proposed a method to calculate both the integer and non-integer parts of the pulse respiration quotient (<i>PRQ</i> = <i>BBI</i>/<i>RRI</i> = <i>PRQ<sub>int</sub></i> + <i>b1</i> + <i>b2</i>), <i>b1</i> and <i>b2</i> being parts of the border <i>RRIs</i> for each <i>BBI</i>. In this work, we study the correlations between <i>BBI</i> and <i>PRQ</i>, as well as those between <i>BBI</i> and mean <i>RRI</i> within each <i>BBI</i> (<i>mRRI</i>), on a group of twenty subjects in four conditions: in supine and standing positions, in combination with spontaneous and slow breathing. Results show that the <i>BBI</i> vs. <i>PRQ</i> correlations are positive; whereas the breathing regime had little or no effect on the linear regression slopes, body posture did. Two types of scatter plots were obtained with the <i>BBI</i> vs. <i>mRRI</i> correlations: one showed points aggregated around the concurrent <i>PRQ<sub>int</sub></i> lines, while the other showed randomly distributed points. Five out of six of the proposed aggregation measures confirmed the existence of these two cardio-respiratory coupling regimes. We also used <i>b1</i> to study the positions of R pulses relative to the respiration onsets and showed that they were more synchronous with sympathetic activation. Overall, this method should be used in different pathological states. |
| first_indexed | 2024-03-11T09:08:43Z |
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| language | English |
| last_indexed | 2024-03-11T09:08:43Z |
| publishDate | 2023-01-01 |
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| series | Bioengineering |
| spelling | doaj.art-3165425fbcf548c2a0ff9d252511a6502023-11-16T19:10:45ZengMDPI AGBioengineering2306-53542023-01-0110218010.3390/bioengineering10020180Two Operational Modes of Cardio-Respiratory Coupling Revealed by Pulse-Respiration QuotientAleksandar Kalauzi0Zoran Matić1Mirjana M. Platiša2Tijana Bojić3Department for Life Sciences, Institute for Multidisciplinary Research, University of Belgrade, 11030 Belgrade, SerbiaBiomedical Engineering and Technologies, University of Belgrade, 11000 Belgrade, SerbiaInstitute of Biophysics, Faculty of Medicine, University of Belgrade, P.O. Box 22, 11129 Belgrade, SerbiaDepartment of Radiation Chemistry and Physics 030, “VINČA” Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, P.O. Box 522, Mike Petrovića Alasa 12–14, 11000 Belgrade, SerbiaDue to the fact that respiratory breath-to-breath and cardiac intervals between two successive R peaks (<i>BBI</i> and <i>RRI</i>, respectively) are not temporally concurrent, in a previous paper, we proposed a method to calculate both the integer and non-integer parts of the pulse respiration quotient (<i>PRQ</i> = <i>BBI</i>/<i>RRI</i> = <i>PRQ<sub>int</sub></i> + <i>b1</i> + <i>b2</i>), <i>b1</i> and <i>b2</i> being parts of the border <i>RRIs</i> for each <i>BBI</i>. In this work, we study the correlations between <i>BBI</i> and <i>PRQ</i>, as well as those between <i>BBI</i> and mean <i>RRI</i> within each <i>BBI</i> (<i>mRRI</i>), on a group of twenty subjects in four conditions: in supine and standing positions, in combination with spontaneous and slow breathing. Results show that the <i>BBI</i> vs. <i>PRQ</i> correlations are positive; whereas the breathing regime had little or no effect on the linear regression slopes, body posture did. Two types of scatter plots were obtained with the <i>BBI</i> vs. <i>mRRI</i> correlations: one showed points aggregated around the concurrent <i>PRQ<sub>int</sub></i> lines, while the other showed randomly distributed points. Five out of six of the proposed aggregation measures confirmed the existence of these two cardio-respiratory coupling regimes. We also used <i>b1</i> to study the positions of R pulses relative to the respiration onsets and showed that they were more synchronous with sympathetic activation. Overall, this method should be used in different pathological states.https://www.mdpi.com/2306-5354/10/2/180heart rate variabilitypulse respiration quotientslow breathingcardio-respiratory couplingcardio-respiratory synchronizationsympatho-vagal balance |
| spellingShingle | Aleksandar Kalauzi Zoran Matić Mirjana M. Platiša Tijana Bojić Two Operational Modes of Cardio-Respiratory Coupling Revealed by Pulse-Respiration Quotient Bioengineering heart rate variability pulse respiration quotient slow breathing cardio-respiratory coupling cardio-respiratory synchronization sympatho-vagal balance |
| title | Two Operational Modes of Cardio-Respiratory Coupling Revealed by Pulse-Respiration Quotient |
| title_full | Two Operational Modes of Cardio-Respiratory Coupling Revealed by Pulse-Respiration Quotient |
| title_fullStr | Two Operational Modes of Cardio-Respiratory Coupling Revealed by Pulse-Respiration Quotient |
| title_full_unstemmed | Two Operational Modes of Cardio-Respiratory Coupling Revealed by Pulse-Respiration Quotient |
| title_short | Two Operational Modes of Cardio-Respiratory Coupling Revealed by Pulse-Respiration Quotient |
| title_sort | two operational modes of cardio respiratory coupling revealed by pulse respiration quotient |
| topic | heart rate variability pulse respiration quotient slow breathing cardio-respiratory coupling cardio-respiratory synchronization sympatho-vagal balance |
| url | https://www.mdpi.com/2306-5354/10/2/180 |
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