Liquid biopsy of patients with advanced liver fibrosis reveals the association of methylation in CpGs and miRNAs expression with the degree of severity

Introduction and Objective: This study aimed to assess whether the expression of specific miRNAs and the percentage of DNA methylation of the Peroxisomal Proliferator-Activated Receptors (PPAR) α, γ and δ genes in tissue and liquid biopsy from patients with advanced liver fibrosis (F3 and F4) is ass...

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Bibliographic Details
Main Authors: R De la Rosa-Bibiano, R Escutia-Gutiérrez, S Rodríguez-Sanabria, E Cerda-Reyes, JM Aguilar, A Santos, AS Sandoval-Rodríguez, J Armendáriz-Borunda
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Annals of Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268122001338