Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen
Sin Nombre virus (SNV) is an emerging virus that was first discovered in the Four Corners region of the United States in 1993. The virus causes a disease known as Hantavirus Pulmonary Syndrome (HPS), sometimes called Hantavirus Cardiopulmonary Syndrome (HCPS), a life-threatening illness named for th...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Biology |
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| Online Access: | https://www.mdpi.com/2079-7737/12/11/1413 |
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| author | Andrew T. Jacob Benjamin M. Ziegler Stefania M. Farha Lyla R. Vivian Cora A. Zilinski Alexis R. Armstrong Andrew J. Burdette Dia C. Beachboard Christopher C. Stobart |
| author_facet | Andrew T. Jacob Benjamin M. Ziegler Stefania M. Farha Lyla R. Vivian Cora A. Zilinski Alexis R. Armstrong Andrew J. Burdette Dia C. Beachboard Christopher C. Stobart |
| author_sort | Andrew T. Jacob |
| collection | DOAJ |
| description | Sin Nombre virus (SNV) is an emerging virus that was first discovered in the Four Corners region of the United States in 1993. The virus causes a disease known as Hantavirus Pulmonary Syndrome (HPS), sometimes called Hantavirus Cardiopulmonary Syndrome (HCPS), a life-threatening illness named for the predominance of infection of pulmonary endothelial cells. SNV is one of several rodent-borne hantaviruses found in the western hemisphere with the capability of causing this disease. The primary reservoir of SNV is the deer mouse (<i>Peromyscus maniculatus</i>), and the virus is transmitted primarily through aerosolized rodent excreta and secreta. Here, we review the history of SNV emergence and its virus biology and relationship to other New World hantaviruses, disease, treatment, and prevention options. |
| first_indexed | 2024-03-09T17:00:20Z |
| format | Article |
| id | doaj.art-316851d2e2e04c4ab27ef5fb6b759b2f |
| institution | Directory Open Access Journal |
| issn | 2079-7737 |
| language | English |
| last_indexed | 2024-03-09T17:00:20Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biology |
| spelling | doaj.art-316851d2e2e04c4ab27ef5fb6b759b2f2023-11-24T14:30:19ZengMDPI AGBiology2079-77372023-11-011211141310.3390/biology12111413Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic PathogenAndrew T. Jacob0Benjamin M. Ziegler1Stefania M. Farha2Lyla R. Vivian3Cora A. Zilinski4Alexis R. Armstrong5Andrew J. Burdette6Dia C. Beachboard7Christopher C. Stobart8Department of Biological Sciences, Butler University, Indianapolis, IN 46208, USADepartment of Biology, DeSales University, Center Valley, PA 18034, USADepartment of Biological Sciences, Butler University, Indianapolis, IN 46208, USADepartment of Biological Sciences, Butler University, Indianapolis, IN 46208, USADepartment of Biology, DeSales University, Center Valley, PA 18034, USADepartment of Biology, DeSales University, Center Valley, PA 18034, USADepartment of Biological Sciences, Butler University, Indianapolis, IN 46208, USADepartment of Biology, DeSales University, Center Valley, PA 18034, USADepartment of Biological Sciences, Butler University, Indianapolis, IN 46208, USASin Nombre virus (SNV) is an emerging virus that was first discovered in the Four Corners region of the United States in 1993. The virus causes a disease known as Hantavirus Pulmonary Syndrome (HPS), sometimes called Hantavirus Cardiopulmonary Syndrome (HCPS), a life-threatening illness named for the predominance of infection of pulmonary endothelial cells. SNV is one of several rodent-borne hantaviruses found in the western hemisphere with the capability of causing this disease. The primary reservoir of SNV is the deer mouse (<i>Peromyscus maniculatus</i>), and the virus is transmitted primarily through aerosolized rodent excreta and secreta. Here, we review the history of SNV emergence and its virus biology and relationship to other New World hantaviruses, disease, treatment, and prevention options.https://www.mdpi.com/2079-7737/12/11/1413Sin Nombre virusAndes virushantavirusHPSHCPS |
| spellingShingle | Andrew T. Jacob Benjamin M. Ziegler Stefania M. Farha Lyla R. Vivian Cora A. Zilinski Alexis R. Armstrong Andrew J. Burdette Dia C. Beachboard Christopher C. Stobart Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen Biology Sin Nombre virus Andes virus hantavirus HPS HCPS |
| title | Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen |
| title_full | Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen |
| title_fullStr | Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen |
| title_full_unstemmed | Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen |
| title_short | Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen |
| title_sort | sin nombre virus and the emergence of other hantaviruses a review of the biology ecology and disease of a zoonotic pathogen |
| topic | Sin Nombre virus Andes virus hantavirus HPS HCPS |
| url | https://www.mdpi.com/2079-7737/12/11/1413 |
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