Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach?
Background: Maximum intensity projection (MIP) CT image reconstruction is a beneficial diagnostic tool in paediatric radiology and can help to distinguish between small pulmonary nodules and adjacent vessels or pulmonary scars. Objectives: The purpose of this study was to determine the optimal MIP s...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2016-12-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0378603X16301759 |
| _version_ | 1818864208667738112 |
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| author | Mehmet Burak Özkan, MD Sebastian Tscheuner, MD Elif Ozkan, MD |
| author_facet | Mehmet Burak Özkan, MD Sebastian Tscheuner, MD Elif Ozkan, MD |
| author_sort | Mehmet Burak Özkan, MD |
| collection | DOAJ |
| description | Background: Maximum intensity projection (MIP) CT image reconstruction is a beneficial diagnostic tool in paediatric radiology and can help to distinguish between small pulmonary nodules and adjacent vessels or pulmonary scars.
Objectives: The purpose of this study was to determine the optimal MIP slice thickness and reconstruction plane for pulmonary nodule detection in paediatric patients.
Materials and methods: Fifty-five paediatric patients with suspected nodules less than 5 mm who were diagnosed with extra-pulmonary malignancy and underwent multidetector computed tomography (MDCT) of the thorax were evaluated. Multiplanar CT 5 mm MIP reconstruction (axial-coronal-sagittal), 2 mm axial-coronal MIPs, and 1-mm and 5-mm axial source slices, were interpreted independently by three blinded radiologists. The axial -1 mm slices were accepted as the gold standard method as the result of retrospective consensus session in order to get comparison with similar studies. The number of nodules, size and location, distance from pleura, overall time taken and confidence were recorded separately for each observer.
Results: Receiver operating characteristic (ROC) analysis showed significant advantages of MIP images over averaged images. With high significance (p < 0.001), coronal 5 mm MIP reconstructions were found to be most advantageous over conventional reconstruction techniques. Mean reading time was fastest in axial 5 mm MIP images.
Conclusions: Compared to conventional paediatric chest CT reconstruction techniques, detection of pulmonary nodules with diameters smaller than 5 mm was found to be most sensitive in 5 mm coronal MIP images.
Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach? |
| first_indexed | 2024-12-19T10:28:00Z |
| format | Article |
| id | doaj.art-316854b235e6424cb3757fa6f0387a61 |
| institution | Directory Open Access Journal |
| issn | 0378-603X |
| language | English |
| last_indexed | 2024-12-19T10:28:00Z |
| publishDate | 2016-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-316854b235e6424cb3757fa6f0387a612022-12-21T20:25:49ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2016-12-014741629163710.1016/j.ejrnm.2016.09.008Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach?Mehmet Burak Özkan, MD0Sebastian Tscheuner, MD1Elif Ozkan, MD2Department of Pediatric Radiology Department, Dr Sami Ulus Research and Training Hospital, Altindag, Ankara, TurkeyDepartment of Pediatric Radiology, Graz, AustriaDepartment of Pediatrics, Sami Ulus Hospital, Ankara, TurkeyBackground: Maximum intensity projection (MIP) CT image reconstruction is a beneficial diagnostic tool in paediatric radiology and can help to distinguish between small pulmonary nodules and adjacent vessels or pulmonary scars. Objectives: The purpose of this study was to determine the optimal MIP slice thickness and reconstruction plane for pulmonary nodule detection in paediatric patients. Materials and methods: Fifty-five paediatric patients with suspected nodules less than 5 mm who were diagnosed with extra-pulmonary malignancy and underwent multidetector computed tomography (MDCT) of the thorax were evaluated. Multiplanar CT 5 mm MIP reconstruction (axial-coronal-sagittal), 2 mm axial-coronal MIPs, and 1-mm and 5-mm axial source slices, were interpreted independently by three blinded radiologists. The axial -1 mm slices were accepted as the gold standard method as the result of retrospective consensus session in order to get comparison with similar studies. The number of nodules, size and location, distance from pleura, overall time taken and confidence were recorded separately for each observer. Results: Receiver operating characteristic (ROC) analysis showed significant advantages of MIP images over averaged images. With high significance (p < 0.001), coronal 5 mm MIP reconstructions were found to be most advantageous over conventional reconstruction techniques. Mean reading time was fastest in axial 5 mm MIP images. Conclusions: Compared to conventional paediatric chest CT reconstruction techniques, detection of pulmonary nodules with diameters smaller than 5 mm was found to be most sensitive in 5 mm coronal MIP images. Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach?http://www.sciencedirect.com/science/article/pii/S0378603X16301759Maximum intensity projectionMIPPulmonary nodulePaediatric radiologyOncologyCT |
| spellingShingle | Mehmet Burak Özkan, MD Sebastian Tscheuner, MD Elif Ozkan, MD Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach? The Egyptian Journal of Radiology and Nuclear Medicine Maximum intensity projection MIP Pulmonary nodule Paediatric radiology Oncology CT |
| title | Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach? |
| title_full | Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach? |
| title_fullStr | Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach? |
| title_full_unstemmed | Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach? |
| title_short | Diagnostic accuracy of MIP slice modalities for small pulmonary nodules in paediatric oncology patients revisited: What is additional from the paediatric radiologist approach? |
| title_sort | diagnostic accuracy of mip slice modalities for small pulmonary nodules in paediatric oncology patients revisited what is additional from the paediatric radiologist approach |
| topic | Maximum intensity projection MIP Pulmonary nodule Paediatric radiology Oncology CT |
| url | http://www.sciencedirect.com/science/article/pii/S0378603X16301759 |
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