Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses—Preliminary Study
Skeletal muscle is considered to be the largest endocrine organ determining the maintenance of energy homeostasis. Adaptive changes in skeletal muscles in response to physical exercise influence the production as well as secretion of myokines, which are bioactive factors that play a crucial role in...
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MDPI AG
2020-12-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/10/12/2268 |
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| author | Sylwester Kowalik Anna Wiśniewska Witold Kędzierski Iwona Janczarek |
| author_facet | Sylwester Kowalik Anna Wiśniewska Witold Kędzierski Iwona Janczarek |
| author_sort | Sylwester Kowalik |
| collection | DOAJ |
| description | Skeletal muscle is considered to be the largest endocrine organ determining the maintenance of energy homeostasis. Adaptive changes in skeletal muscles in response to physical exercise influence the production as well as secretion of myokines, which are bioactive factors that play a crucial role in energy expenditure processes. The aim of the study was to investigate the impact of two different types of exercise on the circulating level of two of these, myostatin and irisin, in trained horses. Twenty purebred Arabian horses were involved in the study: 10 three-year-old horses trained on the racetrack and 10 endurance horses aged 7.4 ± 1.9 years. The horses from both groups were regularly trained throughout the entire season, during which they also participated in Polish National competitions. To assess the influence of the training sessions on plasma myostatin and irisin concentrations, blood samples taken at rest and 30 min after the end of exercise were analyzed. In the studied horses, the single bout of exercise did not influence plasma irisin but induced an increase in plasma myostatin concentration. In racehorses, plasma irisin concentration decreased with the length of the training season. Plasma myostatin was higher in endurance horses than in three-year-old racehorses. Lack of exercise-induced fluctuation in circulating irisin in studied horses suggests that myostatin released in response to exercise provides a negative feedback signal to irisin release. |
| first_indexed | 2024-03-10T14:24:03Z |
| format | Article |
| id | doaj.art-3168eb51b7e04b539cd5eead25a2f75f |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T14:24:03Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-3168eb51b7e04b539cd5eead25a2f75f2023-11-20T23:08:27ZengMDPI AGAnimals2076-26152020-12-011012226810.3390/ani10122268Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses—Preliminary StudySylwester Kowalik0Anna Wiśniewska1Witold Kędzierski2Iwona Janczarek3Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, ul. Akademicka 12, 20-033 Lublin, PolandDepartment of Horse Breeding and Use, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, ul. Akademicka 13, 20-950 Lublin, PolandDepartment of Biochemistry, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, ul. Akademicka 12, 20-033 Lublin, PolandDepartment of Horse Breeding and Use, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, ul. Akademicka 13, 20-950 Lublin, PolandSkeletal muscle is considered to be the largest endocrine organ determining the maintenance of energy homeostasis. Adaptive changes in skeletal muscles in response to physical exercise influence the production as well as secretion of myokines, which are bioactive factors that play a crucial role in energy expenditure processes. The aim of the study was to investigate the impact of two different types of exercise on the circulating level of two of these, myostatin and irisin, in trained horses. Twenty purebred Arabian horses were involved in the study: 10 three-year-old horses trained on the racetrack and 10 endurance horses aged 7.4 ± 1.9 years. The horses from both groups were regularly trained throughout the entire season, during which they also participated in Polish National competitions. To assess the influence of the training sessions on plasma myostatin and irisin concentrations, blood samples taken at rest and 30 min after the end of exercise were analyzed. In the studied horses, the single bout of exercise did not influence plasma irisin but induced an increase in plasma myostatin concentration. In racehorses, plasma irisin concentration decreased with the length of the training season. Plasma myostatin was higher in endurance horses than in three-year-old racehorses. Lack of exercise-induced fluctuation in circulating irisin in studied horses suggests that myostatin released in response to exercise provides a negative feedback signal to irisin release.https://www.mdpi.com/2076-2615/10/12/2268hormonesirisinmyostatinexerciseenduranceracehorses |
| spellingShingle | Sylwester Kowalik Anna Wiśniewska Witold Kędzierski Iwona Janczarek Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses—Preliminary Study Animals hormones irisin myostatin exercise endurance racehorses |
| title | Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses—Preliminary Study |
| title_full | Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses—Preliminary Study |
| title_fullStr | Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses—Preliminary Study |
| title_full_unstemmed | Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses—Preliminary Study |
| title_short | Concentrations of Circulating Irisin and Myostatin in Race and Endurace Purebred Arabian Horses—Preliminary Study |
| title_sort | concentrations of circulating irisin and myostatin in race and endurace purebred arabian horses preliminary study |
| topic | hormones irisin myostatin exercise endurance racehorses |
| url | https://www.mdpi.com/2076-2615/10/12/2268 |
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