Methanol Extract of Aerial Parts of <i>Pavetta indica</i> L. Enhances the Cytotoxic Effect of Doxorubicin and Induces Radiation Sensitization in MDA-MB-231 Triple-Negative Breast Cancer Cells

Methanol Extract of Aerial Parts of <i>Pavetta indica</i> L. Enhances the Cytotoxic Effect of Doxorubicin and Induces Radiation Sensitization in MDA-MB-231 Triple-Negative Breast Cancer Cells

<i>Pavetta indica</i> L. is used in traditional medicine for the treatment of various diseases including hemorrhoids, headache, urinary conditions, ulcerated nose, and dropsy. However, no study has evaluated the anticancer effect of <i>P. indica</i> L. In this study, we found...

Full description

Bibliographic Details
Main Authors:	Yen Thi-Kim Nguyen, Jeong Yong Moon, Ji-yeon Ryu, Sangmi Eum, Tran The Bach, Somi Kim Cho
Format:	Article
Language:	English
Published:	MDPI AG 2019-06-01
Series:	Molecules
Subjects:	<i>Pavetta indica</i> L. triple-negative breast cancer cells resistance gas chromatography-mass spectrometry analysis synergistic effect 5,6-dehydrokawain
Online Access:	https://www.mdpi.com/1420-3049/24/12/2273

Similar Items

Pollination ecology and fruiting behavior of Pavetta indica L. (Rubiaceae), a keystone shrub species in the southern Eastern Ghats forest, Andhra Pradesh, India
by: A.J. Solomon Raju, et al.
Published: (2016-08-01)

Anti-Obesity Effects of Hispidin and Alpinia zerumbet Bioactives in 3T3-L1 Adipocytes
by: Pham Thi Be Tu, et al.
Published: (2014-10-01)

<i>Alpinia zerumbet</i> (Pers.): Food and Medicinal Plant with Potential In Vitro and In Vivo Anti-Cancer Activities
by: Maram Hussein Zahra, et al.
Published: (2019-07-01)

5,6-dehydrokawain improves glycaemic control by modulating AMPK target genes in Drosophila with a high-sucrose diet-induced hyperglycaemia
by: Hadiza Muhammad Maiturare, et al.
Published: (2022-05-01)

Antimicrobial test of five ethnomedicinal plants in an ancestral forest area
by: M.B. Bandibas, et al.
Published: (2017-09-01)

Chemical constituents and antimycobacterial studies of the leaf extracts of Pavetta crassipes K. Schum
by: Nneka N. Ibekwe, et al.
Published: (2018-04-01)

Effect of <it>Alpinia zerumbet</it> components on antioxidant and skin diseases-related enzymes
by: Chompoo Jamnian, et al.
Published: (2012-07-01)

Chemical Composition and Antibacterial, Antioxidant, and Cytotoxic Activities of Essential Oils from Leaves and Stems of <i>Aeschynomene indica</i> L.
by: Linjie Feng, et al.
Published: (2024-07-01)

Chitotriose Enhanced Antitumor Activity of Doxorubicin through <i>Egr1</i> Upregulation in MDA-MB-231 Cells
by: Heng Li, et al.
Published: (2023-12-01)

<i>Azadirachta indica</i> A. Juss. In Vivo Toxicity—An Updated Review
by: Teresa M. Braga, et al.
Published: (2021-01-01)

The chemosensitizer ferulic acid enhances epirubicin-induced apoptosis in MDA-MB-231 cells
by: Wei-Jia Cheng, et al.
Published: (2020-10-01)

Acalypha indica Linn: Biogenic synthesis of silver and gold nanoparticles and their cytotoxic effects against MDA-MB-231, human breast cancer cells
by: C. Krishnaraj, et al.
Published: (2014-12-01)

Poisonous Plants Seem to Affect Livestock in the Borana, Southern Ethiopia: An Ethnic-Toxicological Approach
by: Kumbe A, et al.
Published: (2024-02-01)

Identification of <i>Indica–Japonica</i> Attributes and Analysis of Heterosis Using InDel Markers
by: Lingling Huang, et al.
Published: (2024-11-01)

Sustainable Production of Insecticidal Compounds from <i>Persea indica</i>
by: Azucena Gonzalez-Coloma, et al.
Published: (2022-02-01)

Pharmacological Activity of <i>Garcinia indica</i> (Kokum): An Updated Review
by: Sung Ho Lim, et al.
Published: (2021-12-01)

<i>Neofusicoccum batangarum</i> Causing Dieback of Mango (<i>Mangifera indica</i>) in Florida
by: Alina S. Puig, et al.
Published: (2021-09-01)

Integrated Management of Chive Gnats (<i>Bradysia odoriphaga</i> Yang & Zhang) in Chives Using Entomopathogenic Nematodes and Low-Toxicity Insecticides
by: Xun Yan, et al.
Published: (2019-06-01)

Comparative Assessment of the Apoptotic Potential of Silver Nanoparticles Synthesized by Bacillus Tequilensis and Calocybe Indica in MDA-MB-231 Human Breast Cancer Cells: Targeting p53 for Anticancer Therapy [Corrigendum]
by: Gurunathan S, et al.
Published: (2022-11-01)

Morin Sensitizes MDA-MB-231 Triple-Negative Breast Cancer Cells to Doxorubicin Cytotoxicity by Suppressing FOXM1 and Attenuating EGFR/STAT3 Signaling Pathways
by: Sushma Maharjan, et al.
Published: (2023-04-01)

In Vitro Antibacterial Activity of Green Synthesized Silver Nanoparticles Using <i>Azadirachta indica</i> Aqueous Leaf Extract against MDR Pathogens
by: Omaish Alqahtani, et al.
Published: (2022-10-01)

The Influence of <i>Piriformospora indica</i> Colonization on the Root Development and Growth of <i>Cerasus humilis</i> Cuttings
by: Lu Yin, et al.
Published: (2024-05-01)

Effects of Maturation on Antibacterial Properties of Vietnamese Mango (<i>Mangifera indica</i>) Leaves
by: Hai Thanh Nguyen, et al.
Published: (2024-03-01)

Gastroprotective Effect of <i>Anisomeles indica</i> on Aspirin-Induced Gastric Ulcer in Mice
by: Hsiu-Man Lien, et al.
Published: (2022-11-01)

Co-Application of Silver Nanoparticles and Symbiotic Fungus <i>Piriformospora indica</i> Improves Secondary Metabolite Production in Black Rice
by: Shikha Solanki, et al.
Published: (2023-02-01)

The Current Status, Bioactivity, Food, and Pharmaceutical Approaches of <i>Calocybe indica</i>: A Review
by: Meghna Shashikant, et al.
Published: (2022-06-01)

<i>Tamarindus indica</i> Extract as a Promising Antimicrobial and Antivirulence Therapy
by: Mohamed F. Ghaly, et al.
Published: (2023-02-01)

Biodiesel Production from Alkali-Catalyzed Transesterification of <i>Tamarindus indica</i> Seed Oil and Optimization of Process Conditions
by: Noreen Sajjad, et al.
Published: (2022-05-01)

Inhibition of Advanced Glycation End-Products by <i>Tamarindus indica</i> and <i>Mitragyna inermis</i> Extracts and Effects on Human Hepatocyte and Fibroblast Viability
by: Relwendé Justin Ouédraogo, et al.
Published: (2023-01-01)

Coumarinolignans with Reactive Oxygen Species (ROS) and NF-κB Inhibitory Activities from the Roots of <i>Waltheria indica</i>
by: Feifei Liu, et al.
Published: (2022-05-01)

<i>Serendipita indica</i> Promotes the Growth of Tartary Buckwheat by Stimulating Hormone Synthesis, Metabolite Production, and Increasing Systemic Resistance
by: Meijia Zheng, et al.
Published: (2023-11-01)

Management of <i>Eleusine indica</i> (L.) Gaertn Resistance to Glyphosate Herbicide in Indonesia
by: Denny Kurniadie, et al.
Published: (2023-06-01)

Activation of Nuclear Factor Erythroid 2-Related Factor-2 by Oxylipin from <i>Mangifera indica</i> Leaves
by: Atif Ali Khan Khalil, et al.
Published: (2024-09-01)

Pharmacognostic Evaluation, Chemical Characterization, and Antibacterial Activity of <i>Bassia indica</i> (Wight) A.J. Scott
by: Fayyaz Anjum, et al.
Published: (2024-06-01)

Isolation, NMR Characterization, and Bioactivity of a Flavonoid Triglycoside from <i>Anthyllis henoniana</i> Stems: Antioxidant and Antiproliferative Effects on MDA-MB-231 Breast Cancer Cells
by: Amani Ayachi, et al.
Published: (2024-06-01)

Formation of Stable Cruciform Assembly of Gold Nanoparticles from <i>Cannabis indica</i> Leaves
by: Anjul Khadria, et al.
Published: (2022-07-01)

Biochemical and Functional Characterization of Anthocyanidin Reductase (ANR) from <i>Mangifera indica</i> L.
by: Lin Tan, et al.
Published: (2018-11-01)

Biosynthesis of Silver Nanoparticles from <i>Duchesnea indica</i> Extracts Using Different Solvents and Their Antibacterial Activity
by: Se-Min Kim, et al.
Published: (2023-06-01)

An Insight into In Vitro Antioxidant, Antimicrobial, Cytotoxic, and Apoptosis Induction Potential of Mangiferin, a Bioactive Compound Derived from <i>Mangifera indica</i>
by: Ramy S. Yehia, et al.
Published: (2023-04-01)

Use of <i>Piriformospora indica</i> to Promote Growth of Strawberry Daughter Plants
by: Wei Liu, et al.
Published: (2022-04-01)