CD34+DNAM-1brightCXCR4+ haemopoietic precursors circulate after chemotherapy, seed lung tissue and generate functional innate-like T cells and NK cells

CD34+DNAM-1brightCXCR4+ haemopoietic precursors circulate after chemotherapy, seed lung tissue and generate functional innate-like T cells and NK cells

BackgroundThere is little information on the trajectory and developmental fate of Lin-CD34+DNAM-1bright CXCR4+ progenitors exiting bone marrow during systemic inflammation.ObjectiveTo study Lin-CD34+DNAM-1bright CXCR4+ cell circulation in cancer patients, to characterize their entry into involved lu...

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Bibliographic Details
Main Authors: Carola Perrone, Federica Bozzano, Maria Giovanna Dal Bello, Genny Del Zotto, Francesca Antonini, Enrico Munari, Enrico Maggi, Francesca Moretta, Alireza Hajabbas Farshchi, Gianluca Pariscenti, Marco Tagliamento, Carlo Genova, Lorenzo Moretta, Andrea De Maria
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
CD34+DNAM-1brightCXCR4+
CD34
NK cell
lung tumor
NSCLC
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1332781/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1332781/full

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