Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical Trial
Background: Postprandial glycemic excursions are associated with impairment control of diabetes mellitus. Long-term consumption of flaxseed can lower blood glucose levels; however, its effects on the postprandial glycemic response remain unknown. Therefore, this study aimed to evaluate the acute eff...
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| Format: | Article |
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MDPI AG
2022-09-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/18/3736 |
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| author | Fernanda Duarte Moreira Caio Eduardo Gonçalves Reis Alexis Fonseca Welker Andrea Donatti Gallassi |
| author_facet | Fernanda Duarte Moreira Caio Eduardo Gonçalves Reis Alexis Fonseca Welker Andrea Donatti Gallassi |
| author_sort | Fernanda Duarte Moreira |
| collection | DOAJ |
| description | Background: Postprandial glycemic excursions are associated with impairment control of diabetes mellitus. Long-term consumption of flaxseed can lower blood glucose levels; however, its effects on the postprandial glycemic response remain unknown. Therefore, this study aimed to evaluate the acute effects of raw flaxseed consumption on the 2 h postprandial glycemic curve in men with type 2 diabetes mellitus (T2DM). Methods: This was a randomized crossover clinical trial. Nineteen men with T2DM were randomly assigned a standardized breakfast without (control) or with a previous intake of 15 g of ground raw golden flaxseed (flax). Glycemia was measured at fasting and postprandial at 15, 30, 45, 60, 90, and 120 min. Palatability markers (visual appeal, smell, and pleasantness of taste) and taste intensity (sweetness, saltiness, bitterness, sourness, and creaminess) were evaluated. Results: The peak glucose rise and the 2 h AUC glycemic response reduced in the flax group by 17% (<i>p</i> = 0.001) and 24% (<i>p</i> < 0.001), respectively. The glucose peak time, palatability, and taste parameters did not differ between the two groups. Conclusions: Ingestion of 15 g of ground raw golden flaxseed before breakfast decreases the 2 h postprandial glycemic response in men with T2DM. |
| first_indexed | 2024-03-09T22:55:58Z |
| format | Article |
| id | doaj.art-31722b1e7c414e3b971719d79cdbba25 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T22:55:58Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-31722b1e7c414e3b971719d79cdbba252023-11-23T18:11:01ZengMDPI AGNutrients2072-66432022-09-011418373610.3390/nu14183736Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical TrialFernanda Duarte Moreira0Caio Eduardo Gonçalves Reis1Alexis Fonseca Welker2Andrea Donatti Gallassi3Coordenação Geral de Atenção às Pessoas com Doenças Crônicas, Ministério da Saúde, Brasília 70058-900, BrazilDepartamento de Nutrição, Universidade de Brasília, Brasília 70910-900, BrazilPrograma de Pós-Graduação em Ciências e Tecnologias em Saúde, Universidade de Brasília, Brasília 72220-275, BrazilPrograma de Pós-Graduação em Ciências e Tecnologias em Saúde, Universidade de Brasília, Brasília 72220-275, BrazilBackground: Postprandial glycemic excursions are associated with impairment control of diabetes mellitus. Long-term consumption of flaxseed can lower blood glucose levels; however, its effects on the postprandial glycemic response remain unknown. Therefore, this study aimed to evaluate the acute effects of raw flaxseed consumption on the 2 h postprandial glycemic curve in men with type 2 diabetes mellitus (T2DM). Methods: This was a randomized crossover clinical trial. Nineteen men with T2DM were randomly assigned a standardized breakfast without (control) or with a previous intake of 15 g of ground raw golden flaxseed (flax). Glycemia was measured at fasting and postprandial at 15, 30, 45, 60, 90, and 120 min. Palatability markers (visual appeal, smell, and pleasantness of taste) and taste intensity (sweetness, saltiness, bitterness, sourness, and creaminess) were evaluated. Results: The peak glucose rise and the 2 h AUC glycemic response reduced in the flax group by 17% (<i>p</i> = 0.001) and 24% (<i>p</i> < 0.001), respectively. The glucose peak time, palatability, and taste parameters did not differ between the two groups. Conclusions: Ingestion of 15 g of ground raw golden flaxseed before breakfast decreases the 2 h postprandial glycemic response in men with T2DM.https://www.mdpi.com/2072-6643/14/18/3736dietary fiberdiabetes mellitusflaxseedpostprandial blood glucosecomplex carbohydrates |
| spellingShingle | Fernanda Duarte Moreira Caio Eduardo Gonçalves Reis Alexis Fonseca Welker Andrea Donatti Gallassi Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical Trial Nutrients dietary fiber diabetes mellitus flaxseed postprandial blood glucose complex carbohydrates |
| title | Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical Trial |
| title_full | Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical Trial |
| title_fullStr | Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical Trial |
| title_full_unstemmed | Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical Trial |
| title_short | Acute Flaxseed Intake Reduces Postprandial Glycemia in Subjects with Type 2 Diabetes: A Randomized Crossover Clinical Trial |
| title_sort | acute flaxseed intake reduces postprandial glycemia in subjects with type 2 diabetes a randomized crossover clinical trial |
| topic | dietary fiber diabetes mellitus flaxseed postprandial blood glucose complex carbohydrates |
| url | https://www.mdpi.com/2072-6643/14/18/3736 |
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