Neuroprotective effects of osmotin in Parkinson’s disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways

Neuroprotective effects of osmotin in Parkinson’s disease-associated pathology via the AdipoR1/MAPK/AMPK/mTOR signaling pathways

Abstract Background Parkinson’s disease (PD) is the second most frequent age-related neurodegenerative disorder and is characterized by the loss of dopaminergic neurons. Both environmental and genetic aspects are involved in the pathogenesis of PD. Osmotin is a structural and functional homolog of a...

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Bibliographic Details
Main Authors: Jun Sung Park, Kyonghwan Choe, Hyeon Jin Lee, Tae Ju Park, Myeong Ok Kim
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Biomedical Science
Subjects:
Parkinson’s disease
Osmotin
α-Synuclein
Dopaminergic neuron
Neuroinflammation
Online Access:https://doi.org/10.1186/s12929-023-00961-z

Internet

https://doi.org/10.1186/s12929-023-00961-z

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