Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies.
Evidence is rapidly mounting that transposable element (TE) expression and replication may impact biology more widely than previously thought. This includes potential effects on normal physiology of somatic tissues and dysfunctional impacts in diseases associated with aging, such as cancer and neuro...
Main Authors: | Yung-Heng Chang, Richard M Keegan, Lisa Prazak, Josh Dubnau |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-05-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000278 |
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