Low level TGF-β1-treated Umbilical mesenchymal stem cells attenuates microgliosis and neuropathic pain in chronic constriction injury by exosomes/lncRNA UCA1／miR-96-5p／FOXO3a

Low level TGF-β1-treated Umbilical mesenchymal stem cells attenuates microgliosis and neuropathic pain in chronic constriction injury by exosomes/lncRNA UCA1／miR-96-5p／FOXO3a

Neuropathic pain is a chronic pain state that usually caused by injuries in peripheral or central nerve. Inhibition of spinal microglial response is a promising treatment of neuropathic pain caused by peripheral nerve injury. In recent years, mesenchymal stem cells (MSCs) that characterized with mul...

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Bibliographic Details
Main Authors: Chunlin Mou, Zhengnan Li, Nian Liu, Ling Ni, YongSheng Xu
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
Neuropathic pain
Microgliosis
TGF-β1
Mesenchymal stem cells
Exosomes
lncRNA UCA1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823000584

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