Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones
Intermittent fasting has become an increasingly popular strategy in losing weight and associated reduction in obesity-related medical complications. Overwhelming studies support metabolic improvements from intermittent fasting in blood glucose levels, cardiac and brain function, and other health ben...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Endocrine Society
2021-08-01
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| Series: | Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.e-enm.org/upload/pdf/enm-2021-405.pdf |
| _version_ | 1818755996428795904 |
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| author | Bo Hye Kim Yena Joo Min-Seon Kim Han Kyoung Choe Qingchun Tong Obin Kwon |
| author_facet | Bo Hye Kim Yena Joo Min-Seon Kim Han Kyoung Choe Qingchun Tong Obin Kwon |
| author_sort | Bo Hye Kim |
| collection | DOAJ |
| description | Intermittent fasting has become an increasingly popular strategy in losing weight and associated reduction in obesity-related medical complications. Overwhelming studies support metabolic improvements from intermittent fasting in blood glucose levels, cardiac and brain function, and other health benefits, in addition to weight loss. However, concerns have also been raised on side effects including muscle loss, ketosis, and electrolyte imbalance. Of particular concern, the effect of intermittent fasting on hormonal circadian rhythms has received little attention. Given the known importance of circadian hormonal changes to normal physiology, potential detrimental effects by dysregulation of hormonal changes deserve careful discussions. In this review, we describe the changes in circadian rhythms of hormones caused by intermittent fasting. We covered major hormones commonly pathophysiologically involved in clinical endocrinology, including insulin, thyroid hormones, and glucocorticoids. Given that intermittent fasting could alter both the level and frequency of hormone secretion, decisions on practicing intermittent fasting should take more considerations on potential detrimental consequences versus beneficial effects pertaining to individual health conditions. |
| first_indexed | 2024-12-18T05:48:01Z |
| format | Article |
| id | doaj.art-317a7afe1bb5412891cebe5705f13965 |
| institution | Directory Open Access Journal |
| issn | 2093-596X 2093-5978 |
| language | English |
| last_indexed | 2024-12-18T05:48:01Z |
| publishDate | 2021-08-01 |
| publisher | Korean Endocrine Society |
| record_format | Article |
| series | Endocrinology and Metabolism |
| spelling | doaj.art-317a7afe1bb5412891cebe5705f139652022-12-21T21:18:58ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782021-08-0136474575610.3803/EnM.2021.4052205Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of HormonesBo Hye Kim0Yena Joo1Min-Seon Kim2Han Kyoung Choe3Qingchun Tong4Obin Kwon5 Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea Seoul National University College of Medicine, Seoul, Korea Division of Endocrinology and Metabolism, Department of Internal Medicine, Diabetes Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Department of Brain and Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Korea Brown Institute of Molecular Medicine and Department of Neurobiology and Anatomy, McGovern Medical School of UTHealth, and MD Anderson Cancer Center & UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, KoreaIntermittent fasting has become an increasingly popular strategy in losing weight and associated reduction in obesity-related medical complications. Overwhelming studies support metabolic improvements from intermittent fasting in blood glucose levels, cardiac and brain function, and other health benefits, in addition to weight loss. However, concerns have also been raised on side effects including muscle loss, ketosis, and electrolyte imbalance. Of particular concern, the effect of intermittent fasting on hormonal circadian rhythms has received little attention. Given the known importance of circadian hormonal changes to normal physiology, potential detrimental effects by dysregulation of hormonal changes deserve careful discussions. In this review, we describe the changes in circadian rhythms of hormones caused by intermittent fasting. We covered major hormones commonly pathophysiologically involved in clinical endocrinology, including insulin, thyroid hormones, and glucocorticoids. Given that intermittent fasting could alter both the level and frequency of hormone secretion, decisions on practicing intermittent fasting should take more considerations on potential detrimental consequences versus beneficial effects pertaining to individual health conditions.http://www.e-enm.org/upload/pdf/enm-2021-405.pdfintermittent fastingcircadian rhythminsulinthyroid hormonesglucocorticoids |
| spellingShingle | Bo Hye Kim Yena Joo Min-Seon Kim Han Kyoung Choe Qingchun Tong Obin Kwon Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones Endocrinology and Metabolism intermittent fasting circadian rhythm insulin thyroid hormones glucocorticoids |
| title | Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones |
| title_full | Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones |
| title_fullStr | Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones |
| title_full_unstemmed | Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones |
| title_short | Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones |
| title_sort | effects of intermittent fasting on the circulating levels and circadian rhythms of hormones |
| topic | intermittent fasting circadian rhythm insulin thyroid hormones glucocorticoids |
| url | http://www.e-enm.org/upload/pdf/enm-2021-405.pdf |
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