COMPARATIVE LIGHT OPTICAL AND ELECTRON MICROSCOPIC STUDY OF DYNAMICS FOR NATURAL DEATH OF HEPATIC CELLS

Purpose: the dynamics of natural death for hepatocytes was examined with light optical and electron microscopic methods.Material and Methods: material was the liver of mature rabbits (n=12) and white rats (n=15), that, after common morphological treatment was analyzed under light N 4800 M (x100 imme...

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Main Authors: A. F. Sadriddinov, H. N. Guzacheva, G. O. Hidirova
Format: Article
Language:English
Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 2016-09-01
Series:Медицинский вестник Юга России
Subjects:
Online Access:https://www.medicalherald.ru/jour/article/view/422
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author A. F. Sadriddinov
H. N. Guzacheva
G. O. Hidirova
author_facet A. F. Sadriddinov
H. N. Guzacheva
G. O. Hidirova
author_sort A. F. Sadriddinov
collection DOAJ
description Purpose: the dynamics of natural death for hepatocytes was examined with light optical and electron microscopic methods.Material and Methods: material was the liver of mature rabbits (n=12) and white rats (n=15), that, after common morphological treatment was analyzed under light N 4800 M (x100 immersion) and electron microscope JEM-100S.Results: there were two kinds of apoptosis in the liver of experimental animals. At the first type of apoptosis the large vacuoles occurs in hepatocytes’, cytoplasm at rats, that are changed with small foamy structures (stormy cytoplasm), observing in both animals. At the second type of apoptosis the hepatocyte’ nucleus is decomposed into large fragments, the karyorrhexis (nuclear catastrophe) occurs.Summary: except for apoptosis, the extrusion phenomenon of terminally located hepatocytes was found out in the liver.
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spelling doaj.art-317a92da1de3459b9913a3ce34054c372022-12-22T04:18:29ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762016-09-0103687310.21886/2219-8075-2016-3-68-73349COMPARATIVE LIGHT OPTICAL AND ELECTRON MICROSCOPIC STUDY OF DYNAMICS FOR NATURAL DEATH OF HEPATIC CELLSA. F. Sadriddinov0H. N. Guzacheva1G. O. Hidirova2Histology department of Tashkent pediatric medical InstituteTashkent city family policlinic № 53Histology department of Tashkent pediatric medical InstitutePurpose: the dynamics of natural death for hepatocytes was examined with light optical and electron microscopic methods.Material and Methods: material was the liver of mature rabbits (n=12) and white rats (n=15), that, after common morphological treatment was analyzed under light N 4800 M (x100 immersion) and electron microscope JEM-100S.Results: there were two kinds of apoptosis in the liver of experimental animals. At the first type of apoptosis the large vacuoles occurs in hepatocytes’, cytoplasm at rats, that are changed with small foamy structures (stormy cytoplasm), observing in both animals. At the second type of apoptosis the hepatocyte’ nucleus is decomposed into large fragments, the karyorrhexis (nuclear catastrophe) occurs.Summary: except for apoptosis, the extrusion phenomenon of terminally located hepatocytes was found out in the liver.https://www.medicalherald.ru/jour/article/view/422livermorphologyapoptosisextrusion hepatocytes
spellingShingle A. F. Sadriddinov
H. N. Guzacheva
G. O. Hidirova
COMPARATIVE LIGHT OPTICAL AND ELECTRON MICROSCOPIC STUDY OF DYNAMICS FOR NATURAL DEATH OF HEPATIC CELLS
Медицинский вестник Юга России
liver
morphology
apoptosis
extrusion hepatocytes
title COMPARATIVE LIGHT OPTICAL AND ELECTRON MICROSCOPIC STUDY OF DYNAMICS FOR NATURAL DEATH OF HEPATIC CELLS
title_full COMPARATIVE LIGHT OPTICAL AND ELECTRON MICROSCOPIC STUDY OF DYNAMICS FOR NATURAL DEATH OF HEPATIC CELLS
title_fullStr COMPARATIVE LIGHT OPTICAL AND ELECTRON MICROSCOPIC STUDY OF DYNAMICS FOR NATURAL DEATH OF HEPATIC CELLS
title_full_unstemmed COMPARATIVE LIGHT OPTICAL AND ELECTRON MICROSCOPIC STUDY OF DYNAMICS FOR NATURAL DEATH OF HEPATIC CELLS
title_short COMPARATIVE LIGHT OPTICAL AND ELECTRON MICROSCOPIC STUDY OF DYNAMICS FOR NATURAL DEATH OF HEPATIC CELLS
title_sort comparative light optical and electron microscopic study of dynamics for natural death of hepatic cells
topic liver
morphology
apoptosis
extrusion hepatocytes
url https://www.medicalherald.ru/jour/article/view/422
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