Activation of AMPKα2 Is Not Required for Mitochondrial FAT/CD36 Accumulation during Exercise.

Activation of AMPKα2 Is Not Required for Mitochondrial FAT/CD36 Accumulation during Exercise.

Exercise has been shown to induce the translocation of fatty acid translocase (FAT/CD36), a fatty acid transport protein, to both plasma and mitochondrial membranes. While previous studies have examined signals involved in the induction of FAT/CD36 translocation to sarcolemmal membranes, to date the...

Full description

Bibliographic Details
Main Authors:	Cynthia Monaco, Jamie Whitfield, Swati S Jain, Lawrence L Spriet, Arend Bonen, Graham P Holloway
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4429092?pdf=render

Similar Items

FAT/CD36 expression is not ablated in spontaneously hypertensive rats
by: Arend Bonen, et al.
Published: (2009-04-01)

Sarcolemmal FAT/CD36 in human skeletal muscle colocalizes with caveolin-3 and is more abundant in type 1 than in type 2 fibers
by: Bodil Vistisen, et al.
Published: (2004-04-01)

Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise
by: Janne R. Hingst, et al.
Published: (2020-10-01)

Neurotropin Inhibits Lipid Accumulation by Maintaining Mitochondrial Function in Hepatocytes via AMPK Activation
by: Qinglan Wang, et al.
Published: (2020-08-01)

Limonin, an AMPK Activator, Inhibits Hepatic Lipid Accumulation in High Fat Diet Fed Mice
by: Si-wei Wang, et al.
Published: (2022-01-01)

Activation of AMPKα2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity.
by: Mario Ost, et al.
Published: (2014-01-01)

Mice with Whole-Body Disruption of AMPK-Glycogen Binding Have Increased Adiposity, Reduced Fat Oxidation and Altered Tissue Glycogen Dynamics
by: Natalie R. Janzen, et al.
Published: (2021-09-01)

Conditioning increases the gain of contraction-induced sarcolemmal substrate transport in ultra-endurance racing sled dogs.
by: Michael S Davis, et al.
Published: (2014-01-01)

AMPK, Mitochondrial Function, and Cardiovascular Disease
by: Shengnan Wu, et al.
Published: (2020-07-01)

Vitamin D Mitigates Hepatic Fat Accumulation and Inflammation and Increases SIRT1/AMPK Expression in AML-12 Hepatocytes
by: Eugene Chang
Published: (2024-03-01)

ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis
by: Jian Dong, et al.
Published: (2024-02-01)

Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice
by: Panpan Zhao, et al.
Published: (2023-01-01)

Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis
by: Vanja Panic, et al.
Published: (2020-08-01)

Regulation of the subcellular trafficking of CD36, a major determinant of cardiac fatty acid utilization.
by: Glatz, J, et al.
Published: (2016)

Dietary fat supplementation relieves cold temperature-induced energy stress through AMPK-mediated mitochondrial homeostasis in pigs
by: Wei He, et al.
Published: (2024-04-01)

Copine7 deficiency leads to hepatic fat accumulation via mitochondrial dysfunction
by: Geumbit Hwang, et al.
Published: (2023-11-01)

The role of curcumin in disruption of HIF-1α accumulation to alleviate adipose fibrosis via AMPK-mediated mTOR pathway in high-fat diet fed mice
by: Zhixia Qiu, et al.
Published: (2017-06-01)

Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism
by: Nolan J. Hoffman, et al.
Published: (2020-11-01)

The Herbal Medicine KBH-1 Inhibits Fat Accumulation in 3T3-L1 Adipocytes and Reduces High Fat Diet-Induced Obesity through Regulation of the AMPK Pathway.
by: Ji-Hye Lee, et al.
Published: (2015-01-01)

Exercise and Mitochondrial Dynamics: Keeping in Shape with ROS and AMPK
by: Adam J. Trewin, et al.
Published: (2018-01-01)

AMP-independent activator of AMPK for treatment of mitochondrial disorders.
by: Tereza Moore, et al.
Published: (2020-01-01)

Effects of Isorhamnetin on Adipocyte Mitochondrial Biogenesis and AMPK Activation
by: Mak-Soon Lee, et al.
Published: (2018-07-01)

Mild electrical stimulation increases stress resistance and suppresses fat accumulation via activation of LKB1-AMPK signaling pathway in C. elegans.
by: Shingo Matsuyama, et al.
Published: (2014-01-01)

Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice
by: Licong Yang, et al.
Published: (2019-01-01)

Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro
by: Xiaoyu Cai, et al.
Published: (2023-07-01)

l-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway
by: Taiyang Liao, et al.
Published: (2023-05-01)

Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK
by: Yu Wang, et al.
Published: (2019-11-01)

AMPK is required for exercise to enhance insulin sensitivity in skeletal muscles
by: Jørgen Jensen, et al.
Published: (2017-04-01)

Papain Ameliorates Lipid Accumulation and Inflammation in High-Fat Diet-Induced Obesity Mice and 3T3-L1 Adipocytes via AMPK Activation
by: Yun-Mi Kang, et al.
Published: (2021-09-01)

Pomegranate vinegar beverage reduces visceral fat accumulation in association with AMPK activation in overweight women: A double-blind, randomized, and placebo-controlled trial
by: Ji Eun Park, et al.
Published: (2014-05-01)

NSC48160 targets AMPKα to ameliorate nonalcoholic steatohepatitis by inhibiting lipogenesis and mitochondrial oxidative stress
by: Jiaxin Zhang, et al.
Published: (2024-01-01)

Incorporation of Omega-3 Fatty Acids Into Human Skeletal Muscle Sarcolemmal and Mitochondrial Membranes Following 12 Weeks of Fish Oil Supplementation
by: Christopher J. Gerling, et al.
Published: (2019-03-01)

Xuezhikang alleviates lipid accumulation via AMPK activation in hepatocellular steatosis model
by: Jie Zhang, et al.
Published: (2022-07-01)

Effects of imeglimin on mitochondrial function, AMPK activity, and gene expression in hepatocytes
by: Kaori Hozumi, et al.
Published: (2023-01-01)

Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.
by: Xuan Fu, et al.
Published: (2008-04-01)

FGF19 increases mitochondrial biogenesis and fusion in chondrocytes via the AMPKα-p38/MAPK pathway
by: Shiyi Kan, et al.
Published: (2023-03-01)

PKC-dependent human monocyte adhesion requires AMPK and Syk activation.
by: Mei-Ying Chang, et al.
Published: (2012-01-01)

Chlorogenic Acid Alleviates LPS-Induced Inflammation and Oxidative Stress by Modulating CD36/AMPK/PGC-1α in RAW264.7 Macrophages
by: Tiantian Gu, et al.
Published: (2023-08-01)

AMPK Activation Prevents and Reverses Drug-Induced Mitochondrial and Hepatocyte Injury by Promoting Mitochondrial Fusion and Function.
by: Sun Woo Sophie Kang, et al.
Published: (2016-01-01)

Disrupting AMPK-Glycogen Binding in Mice Increases Carbohydrate Utilization and Reduces Exercise Capacity
by: Natalie R. Janzen, et al.
Published: (2022-03-01)