Design of Iridium N-Heterocyclic Carbene Amino Acid Catalysts for Asymmetric Transfer Hydrogenation of Aryl Ketones

Design of Iridium N-Heterocyclic Carbene Amino Acid Catalysts for Asymmetric Transfer Hydrogenation of Aryl Ketones

A series of chiral complexes of the form Ir(NHC)<sub>2</sub>(aa)(H)(X) (NHC = N-heterocyclic carbene, aa = chelated amino acid, X = halide) was synthesized by oxidative addition of α-amino acids to iridium(I) bis-NHC compounds and screened for asymmetric transfer hydrogenation of ketones...

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Bibliographic Details
Main Authors:	Chad M. Bernier, Joseph S. Merola
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	Catalysts
Subjects:	iridium N-heterocyclic carbene amino acid asymmetric transfer hydrogenation
Online Access:	https://www.mdpi.com/2073-4344/11/6/671

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