Estrogen Receptor and Claudin-6 Might Play Vital Roles for Long-Term Prognosis in Patients With Luminal A Breast Cancer Who Underwent Neoadjuvant Chemotherapy

Estrogen Receptor and Claudin-6 Might Play Vital Roles for Long-Term Prognosis in Patients With Luminal A Breast Cancer Who Underwent Neoadjuvant Chemotherapy

PurposeIt is well-known that the pathological complete response (pCR) rate in patients with luminal A cancer (LAC) is lower than those of other subtypes of breast cancer. The phenotype of cancer often alters after neoadjuvant chemotherapy (NAC) which may be related to hypoxia, and the latter might i...

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Bibliographic Details
Main Authors: Yushi Liu, Ye Kang, Jianyi Li, Yang Zhang, Shi Jia, Qiang Sun, Yan Ma, Jing Zhang, Zhenrong Wang, Yanan Cao, Yang Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
luminal A breast cancer
cycling hypoxia
estrogen receptor
claudin-6
neoadjuvant chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.630065/full

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