Human Papillomavirus and Vaccination in Cervical Cancer
Cervical cancer is not only the most frequently reported cancer among women, but also the most common female genital tract neoplasm in Taiwan. Early detection is effective, because the development, maintenance and progression of precursor lesions (cervical intraepithelial neoplasia [CIN]) evolve slo...
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| Format: | Article |
| Language: | English |
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Elsevier
2007-12-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455908600042 |
| _version_ | 1811239938680684544 |
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| author | Kung-Liahng Wang |
| author_facet | Kung-Liahng Wang |
| author_sort | Kung-Liahng Wang |
| collection | DOAJ |
| description | Cervical cancer is not only the most frequently reported cancer among women, but also the most common female genital tract neoplasm in Taiwan. Early detection is effective, because the development, maintenance and progression of precursor lesions (cervical intraepithelial neoplasia [CIN]) evolve slowly into invasive cancer, typically over a period of more than 10 years. It is now recognized that human papillomavirus (HPV) infection is a necessary cause for over 99% of cervical cancer cases. Advances in the understanding of the causative role of HPV in the etiology of high-grade cervical lesions (CIN 2/3) and cervical cancer have led to the development, evaluation and recommendation of HPV-based technologies for cervical cancer prevention and control. The prevention of HPV infection before the onset of CIN is now possible with recently available prophylactic HPV vaccines, e.g. the quadrivalent Gardasil (Merck & Co., NJ, USA) and bivalent Cervarix (GlaxoSmithKline, London, UK). This review article provides an up-to-date summary of recent studies and available information concerning HPV and vaccination in cervical cancer. |
| first_indexed | 2024-04-12T13:10:30Z |
| format | Article |
| id | doaj.art-318e96bb5ebf4d62a1be770064ec517b |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-04-12T13:10:30Z |
| publishDate | 2007-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-318e96bb5ebf4d62a1be770064ec517b2022-12-22T03:31:53ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592007-12-0146435236210.1016/S1028-4559(08)60004-2Human Papillomavirus and Vaccination in Cervical CancerKung-Liahng WangCervical cancer is not only the most frequently reported cancer among women, but also the most common female genital tract neoplasm in Taiwan. Early detection is effective, because the development, maintenance and progression of precursor lesions (cervical intraepithelial neoplasia [CIN]) evolve slowly into invasive cancer, typically over a period of more than 10 years. It is now recognized that human papillomavirus (HPV) infection is a necessary cause for over 99% of cervical cancer cases. Advances in the understanding of the causative role of HPV in the etiology of high-grade cervical lesions (CIN 2/3) and cervical cancer have led to the development, evaluation and recommendation of HPV-based technologies for cervical cancer prevention and control. The prevention of HPV infection before the onset of CIN is now possible with recently available prophylactic HPV vaccines, e.g. the quadrivalent Gardasil (Merck & Co., NJ, USA) and bivalent Cervarix (GlaxoSmithKline, London, UK). This review article provides an up-to-date summary of recent studies and available information concerning HPV and vaccination in cervical cancer.http://www.sciencedirect.com/science/article/pii/S1028455908600042Cervarixcervical cancerGardasilhuman papillomavirusHPVvaccinesvirus-like particle vaccines |
| spellingShingle | Kung-Liahng Wang Human Papillomavirus and Vaccination in Cervical Cancer Taiwanese Journal of Obstetrics & Gynecology Cervarix cervical cancer Gardasil human papillomavirus HPV vaccines virus-like particle vaccines |
| title | Human Papillomavirus and Vaccination in Cervical Cancer |
| title_full | Human Papillomavirus and Vaccination in Cervical Cancer |
| title_fullStr | Human Papillomavirus and Vaccination in Cervical Cancer |
| title_full_unstemmed | Human Papillomavirus and Vaccination in Cervical Cancer |
| title_short | Human Papillomavirus and Vaccination in Cervical Cancer |
| title_sort | human papillomavirus and vaccination in cervical cancer |
| topic | Cervarix cervical cancer Gardasil human papillomavirus HPV vaccines virus-like particle vaccines |
| url | http://www.sciencedirect.com/science/article/pii/S1028455908600042 |
| work_keys_str_mv | AT kungliahngwang humanpapillomavirusandvaccinationincervicalcancer |