Bisphenol A (BPA) Increases Blood Triglycerides and Low Density Lipoproteins in Albino Wistar Rats
Bisphenol A (BPA) is a component of polycarbonate and other plastics including resins that line food and beverage containers. BPA is known to leach from these products into containerized foods and drinks, and is therefore thought to be routinely ingested. In this present study the possible effect of...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Enugu State University of Science and Technology, ESUT, Enugu, Nigeria.
2017-06-01
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| Series: | Journal of Experimental Research |
| Online Access: | http://www.er-journal.com/papers/Oguazu CE_June_2017_24-27.pdf |
| _version_ | 1819028015927001088 |
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| author | Oguazu CE Ezeonu FC |
| author_facet | Oguazu CE Ezeonu FC |
| author_sort | Oguazu CE |
| collection | DOAJ |
| description | Bisphenol A (BPA) is a component of polycarbonate and other plastics including resins that line food and beverage containers. BPA is known to leach from these products into containerized foods and drinks, and is therefore thought to be routinely ingested. In this present study the possible effect of BPA on blood lipid metabolism were investigated in rats. Female albino Wistar rats were administrated oral doses of 50, 100, 150, 200, and 250 and micro;g BPA/kgbw/day once to determine effect of acute exposure and repeatedly for seven days in another set of test animals to determine the effects of sub-chronic exposure. Following the treatment, serum levels of lipid parameters were examined using the Chemwell Chemical Analyser. All data were expressed as means and plusmn; SD. The result of the study revealed that BPA increased blood triglycerides and LDL of exposed rats at both acute and sub-chronic phases. |
| first_indexed | 2024-12-21T05:51:39Z |
| format | Article |
| id | doaj.art-31903b5ec3d84aa3b9e7f4e11f2ff1a6 |
| institution | Directory Open Access Journal |
| issn | 2315-9650 2502-0524 |
| language | English |
| last_indexed | 2024-12-21T05:51:39Z |
| publishDate | 2017-06-01 |
| publisher | Enugu State University of Science and Technology, ESUT, Enugu, Nigeria. |
| record_format | Article |
| series | Journal of Experimental Research |
| spelling | doaj.art-31903b5ec3d84aa3b9e7f4e11f2ff1a62022-12-21T19:13:57ZengEnugu State University of Science and Technology, ESUT, Enugu, Nigeria.Journal of Experimental Research2315-96502502-05242017-06-01523159650Bisphenol A (BPA) Increases Blood Triglycerides and Low Density Lipoproteins in Albino Wistar RatsOguazu CEEzeonu FCBisphenol A (BPA) is a component of polycarbonate and other plastics including resins that line food and beverage containers. BPA is known to leach from these products into containerized foods and drinks, and is therefore thought to be routinely ingested. In this present study the possible effect of BPA on blood lipid metabolism were investigated in rats. Female albino Wistar rats were administrated oral doses of 50, 100, 150, 200, and 250 and micro;g BPA/kgbw/day once to determine effect of acute exposure and repeatedly for seven days in another set of test animals to determine the effects of sub-chronic exposure. Following the treatment, serum levels of lipid parameters were examined using the Chemwell Chemical Analyser. All data were expressed as means and plusmn; SD. The result of the study revealed that BPA increased blood triglycerides and LDL of exposed rats at both acute and sub-chronic phases.http://www.er-journal.com/papers/Oguazu CE_June_2017_24-27.pdf |
| spellingShingle | Oguazu CE Ezeonu FC Bisphenol A (BPA) Increases Blood Triglycerides and Low Density Lipoproteins in Albino Wistar Rats Journal of Experimental Research |
| title | Bisphenol A (BPA) Increases Blood Triglycerides and Low Density Lipoproteins in Albino Wistar Rats |
| title_full | Bisphenol A (BPA) Increases Blood Triglycerides and Low Density Lipoproteins in Albino Wistar Rats |
| title_fullStr | Bisphenol A (BPA) Increases Blood Triglycerides and Low Density Lipoproteins in Albino Wistar Rats |
| title_full_unstemmed | Bisphenol A (BPA) Increases Blood Triglycerides and Low Density Lipoproteins in Albino Wistar Rats |
| title_short | Bisphenol A (BPA) Increases Blood Triglycerides and Low Density Lipoproteins in Albino Wistar Rats |
| title_sort | bisphenol a bpa increases blood triglycerides and low density lipoproteins in albino wistar rats |
| url | http://www.er-journal.com/papers/Oguazu CE_June_2017_24-27.pdf |
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