IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS
Abstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephali...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/124 |
| _version_ | 1797198149544050688 |
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| author | I. O. Naslednikova N. V. Ryazantseva V. V. Novitsky S. B. Tkachenko A. P. Zima |
| author_facet | I. O. Naslednikova N. V. Ryazantseva V. V. Novitsky S. B. Tkachenko A. P. Zima |
| author_sort | I. O. Naslednikova |
| collection | DOAJ |
| description | Abstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephalitis, and herpes simplex is accompanied by deficient functioning in the T-cell compartment of immune system, and by markedly altered production of immunoregulatory cytokines in peripheral blood mononuclear leukocytes, mainly characterized by Th2 predominance. |
| first_indexed | 2024-03-08T05:51:24Z |
| format | Article |
| id | doaj.art-3190b2b7657c43cc846d6a6b238a145d |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:55:16Z |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-3190b2b7657c43cc846d6a6b238a145d2024-04-22T13:07:33ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0191536010.15789/1563-0625-2007-1-53-60121IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONSI. O. Naslednikova0N. V. Ryazantseva1V. V. Novitsky2S. B. Tkachenko3A. P. Zima4ГОУ ВПО «Сибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию», г. ТомскГОУ ВПО «Сибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию», г. ТомскГОУ ВПО «Сибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию», г. ТомскГОУ ВПО «Сибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию», г. ТомскГОУ ВПО «Сибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию», г. ТомскAbstract. The article is considering certain features of immunopathogenesis exhibited in persistent viral infections, taking into account modern data and recently introduced immunological techniques. It has been revealed that a long-term persistence of hepatitis B and C viruses, tick-borne encephalitis, and herpes simplex is accompanied by deficient functioning in the T-cell compartment of immune system, and by markedly altered production of immunoregulatory cytokines in peripheral blood mononuclear leukocytes, mainly characterized by Th2 predominance.https://www.mimmun.ru/mimmun/article/view/124th1-lymphocytesth2-lymphocytescytokinesviral infections |
| spellingShingle | I. O. Naslednikova N. V. Ryazantseva V. V. Novitsky S. B. Tkachenko A. P. Zima IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS Медицинская иммунология th1-lymphocytes th2-lymphocytes cytokines viral infections |
| title | IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
| title_full | IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
| title_fullStr | IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
| title_full_unstemmed | IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
| title_short | IMBALANCE OF IMMUNOREGULATORY Th1- AND Th2-CYTOKINES IN PERSISTENT VIRAL INFECTIONS |
| title_sort | imbalance of immunoregulatory th1 and th2 cytokines in persistent viral infections |
| topic | th1-lymphocytes th2-lymphocytes cytokines viral infections |
| url | https://www.mimmun.ru/mimmun/article/view/124 |
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