Oxidative stress: an overview of past research and future insights
‘Oxidative stress' (OS) refers to the deviations in redox biology inside biological systems. This term has been used to illustrate the imbalance between oxidants and antioxidants, which has been a subject of extensive research. The obtained findings suggest that many diseases are linked to OS,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | All Life |
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| Online Access: | http://dx.doi.org/10.1080/26895293.2024.2316092 |
| _version_ | 1826862222956036096 |
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| author | Aaser M. Abdelazim Mosleh M. Abomughaid |
| author_facet | Aaser M. Abdelazim Mosleh M. Abomughaid |
| author_sort | Aaser M. Abdelazim |
| collection | DOAJ |
| description | ‘Oxidative stress' (OS) refers to the deviations in redox biology inside biological systems. This term has been used to illustrate the imbalance between oxidants and antioxidants, which has been a subject of extensive research. The obtained findings suggest that many diseases are linked to OS, including diabetes mellitusinflammation, cancers, autoimmune disorders and neurodegenerative diseases. More recently, significant advances in biochemistry and molecular biology have enabled researchers to find master switches of various OS mechanisms and associate OS development to many biological paradigms. In this review, a brief overview of OS research is provided to offer insight into its future directions. Most importantly, the need for a greater understanding of the OS molecular mechanisms and its vital role in the progression of many disorders is emphasized. Likewise, more work is needed on the utility of reactive oxygen species markers as a diagnostic tool. |
| first_indexed | 2024-04-25T02:07:03Z |
| format | Article |
| id | doaj.art-31939cbd9d9a4cfa9ad21c8e1689a94f |
| institution | Directory Open Access Journal |
| issn | 2689-5307 |
| language | English |
| last_indexed | 2025-02-16T20:35:14Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | All Life |
| spelling | doaj.art-31939cbd9d9a4cfa9ad21c8e1689a94f2025-01-20T14:38:00ZengTaylor & Francis GroupAll Life2689-53072024-12-01170110.1080/26895293.2024.23160922316092Oxidative stress: an overview of past research and future insightsAaser M. Abdelazim0Mosleh M. Abomughaid1University of BishaUniversity of Bisha‘Oxidative stress' (OS) refers to the deviations in redox biology inside biological systems. This term has been used to illustrate the imbalance between oxidants and antioxidants, which has been a subject of extensive research. The obtained findings suggest that many diseases are linked to OS, including diabetes mellitusinflammation, cancers, autoimmune disorders and neurodegenerative diseases. More recently, significant advances in biochemistry and molecular biology have enabled researchers to find master switches of various OS mechanisms and associate OS development to many biological paradigms. In this review, a brief overview of OS research is provided to offer insight into its future directions. Most importantly, the need for a greater understanding of the OS molecular mechanisms and its vital role in the progression of many disorders is emphasized. Likewise, more work is needed on the utility of reactive oxygen species markers as a diagnostic tool.http://dx.doi.org/10.1080/26895293.2024.2316092molecular switchesoxidative stressproteomicsredox biology |
| spellingShingle | Aaser M. Abdelazim Mosleh M. Abomughaid Oxidative stress: an overview of past research and future insights All Life molecular switches oxidative stress proteomics redox biology |
| title | Oxidative stress: an overview of past research and future insights |
| title_full | Oxidative stress: an overview of past research and future insights |
| title_fullStr | Oxidative stress: an overview of past research and future insights |
| title_full_unstemmed | Oxidative stress: an overview of past research and future insights |
| title_short | Oxidative stress: an overview of past research and future insights |
| title_sort | oxidative stress an overview of past research and future insights |
| topic | molecular switches oxidative stress proteomics redox biology |
| url | http://dx.doi.org/10.1080/26895293.2024.2316092 |
| work_keys_str_mv | AT aasermabdelazim oxidativestressanoverviewofpastresearchandfutureinsights AT moslehmabomughaid oxidativestressanoverviewofpastresearchandfutureinsights |