LIPID PROFILE AND SERUM INSULIN LEVELS IN GESTATIONAL DIABETES
O bjectives: To evaluate the glucose intolerance, insulin, and lipid profile in w om en who developed gestational Diabetes, compared to healthy pregnancy. Design: Observational study Patients and M ethods: One hundred pregnant women, 50 healthy as control group and 50 already diagnosed gestational...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dow University of Health Sciences
2008-12-01
|
| Series: | Journal of the Dow University of Health Sciences |
| Subjects: | |
| Online Access: | https://jduhs.com/index.php/jduhs/article/view/1278 |
| _version_ | 1797818337952006144 |
|---|---|
| author | Rubina Aziz Tabassum Mahboob |
| author_facet | Rubina Aziz Tabassum Mahboob |
| author_sort | Rubina Aziz |
| collection | DOAJ |
| description |
O bjectives: To evaluate the glucose intolerance, insulin, and lipid profile in w om en who developed gestational Diabetes, compared to healthy pregnancy.
Design: Observational study Patients and M ethods: One hundred pregnant women, 50 healthy as control group and 50 already diagnosed gestational diabetic wom en as study group were selected. Plasm a fasting (FBS) and post prandial glucose
(RBS), serum insulin and serum lipid profile (total lipids, cholesterol, triglycerides, HDL-cholesterol and LDL - cholesterol) of both were monitored. Mean values were compare dusing t-test.
Results: M ean FBS [124.76±4.22 vs. 90.06±1.20 mg/dl], mean RBS [221.38±6.68 vs. 120.32±1.97 mg/dl], insulin [32.10±0.83 vs. 17.88±0.54 |!IU /m l], m ean cholesterol [216.60±5.87 vs. 166.38±3.19 mg/dl], mean triglycerides [189.36±6.76 vs. 106.28±2.85 mg/dl], LDL-cholesterol [131.08±4.73 vs. 102.48±2.18 mg/dl] and total lipids [825.24±16.92 vs. 653.96±15.40 mg/dl] were higher in GDM groups as compared to normal controls (p<0.01). M ean HDL-cholesterol [41.24±0.65 vs. 48.34±0.66 mg/dl] showed significantly lower concentration in GDM group as compared to controls (p<0.01).
Conclusion: M ean insulin and lipid levels, except HDL-cholesterol, were significantly higher in gestational
diabetics compared to controls.
|
| first_indexed | 2024-03-13T09:06:36Z |
| format | Article |
| id | doaj.art-3194118cb29f46c1a46e892c7803104b |
| institution | Directory Open Access Journal |
| issn | 1995-2198 2410-2180 |
| language | English |
| last_indexed | 2024-03-13T09:06:36Z |
| publishDate | 2008-12-01 |
| publisher | Dow University of Health Sciences |
| record_format | Article |
| series | Journal of the Dow University of Health Sciences |
| spelling | doaj.art-3194118cb29f46c1a46e892c7803104b2023-05-28T03:12:19ZengDow University of Health SciencesJournal of the Dow University of Health Sciences1995-21982410-21802008-12-0123LIPID PROFILE AND SERUM INSULIN LEVELS IN GESTATIONAL DIABETESRubina AzizTabassum Mahboob O bjectives: To evaluate the glucose intolerance, insulin, and lipid profile in w om en who developed gestational Diabetes, compared to healthy pregnancy. Design: Observational study Patients and M ethods: One hundred pregnant women, 50 healthy as control group and 50 already diagnosed gestational diabetic wom en as study group were selected. Plasm a fasting (FBS) and post prandial glucose (RBS), serum insulin and serum lipid profile (total lipids, cholesterol, triglycerides, HDL-cholesterol and LDL - cholesterol) of both were monitored. Mean values were compare dusing t-test. Results: M ean FBS [124.76±4.22 vs. 90.06±1.20 mg/dl], mean RBS [221.38±6.68 vs. 120.32±1.97 mg/dl], insulin [32.10±0.83 vs. 17.88±0.54 |!IU /m l], m ean cholesterol [216.60±5.87 vs. 166.38±3.19 mg/dl], mean triglycerides [189.36±6.76 vs. 106.28±2.85 mg/dl], LDL-cholesterol [131.08±4.73 vs. 102.48±2.18 mg/dl] and total lipids [825.24±16.92 vs. 653.96±15.40 mg/dl] were higher in GDM groups as compared to normal controls (p<0.01). M ean HDL-cholesterol [41.24±0.65 vs. 48.34±0.66 mg/dl] showed significantly lower concentration in GDM group as compared to controls (p<0.01). Conclusion: M ean insulin and lipid levels, except HDL-cholesterol, were significantly higher in gestational diabetics compared to controls. https://jduhs.com/index.php/jduhs/article/view/1278G estational diabeteshyperlipidemiainsulin resistancehypertriglyceridemiahigh densitylipoproteins |
| spellingShingle | Rubina Aziz Tabassum Mahboob LIPID PROFILE AND SERUM INSULIN LEVELS IN GESTATIONAL DIABETES Journal of the Dow University of Health Sciences G estational diabetes hyperlipidemia insulin resistance hypertriglyceridemia high density lipoproteins |
| title | LIPID PROFILE AND SERUM INSULIN LEVELS IN GESTATIONAL DIABETES |
| title_full | LIPID PROFILE AND SERUM INSULIN LEVELS IN GESTATIONAL DIABETES |
| title_fullStr | LIPID PROFILE AND SERUM INSULIN LEVELS IN GESTATIONAL DIABETES |
| title_full_unstemmed | LIPID PROFILE AND SERUM INSULIN LEVELS IN GESTATIONAL DIABETES |
| title_short | LIPID PROFILE AND SERUM INSULIN LEVELS IN GESTATIONAL DIABETES |
| title_sort | lipid profile and serum insulin levels in gestational diabetes |
| topic | G estational diabetes hyperlipidemia insulin resistance hypertriglyceridemia high density lipoproteins |
| url | https://jduhs.com/index.php/jduhs/article/view/1278 |
| work_keys_str_mv | AT rubinaaziz lipidprofileandseruminsulinlevelsingestationaldiabetes AT tabassummahboob lipidprofileandseruminsulinlevelsingestationaldiabetes |