Catalytic Addition of Indole-2-Carboxylic Acid to 1-Hexyne
The synthesis of two novel enol esters, namely hex-1-en-2-yl indole-2-carboxylate and hex-1-en-2-yl 1-(hex-1-en-2-yl)-indole-2-carboxylate, is presented. Both compounds were generated by addition of indole-2-carboxylic acid to 1-hexyne employing [RuCl<sub>2</sub>(<i>η</i><...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-07-01
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| Series: | Molbank |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-8599/2020/3/M1145 |
| Summary: | The synthesis of two novel enol esters, namely hex-1-en-2-yl indole-2-carboxylate and hex-1-en-2-yl 1-(hex-1-en-2-yl)-indole-2-carboxylate, is presented. Both compounds were generated by addition of indole-2-carboxylic acid to 1-hexyne employing [RuCl<sub>2</sub>(<i>η</i><sup>6</sup>-<i>p</i>-cymene)(PPh<sub>3</sub>)] and [AuCl(PPh<sub>3</sub>)]/AgPF<sub>6</sub>, respectively, as catalysts. |
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| ISSN: | 1422-8599 |