Catalytic Addition of Indole-2-Carboxylic Acid to 1-Hexyne
The synthesis of two novel enol esters, namely hex-1-en-2-yl indole-2-carboxylate and hex-1-en-2-yl 1-(hex-1-en-2-yl)-indole-2-carboxylate, is presented. Both compounds were generated by addition of indole-2-carboxylic acid to 1-hexyne employing [RuCl<sub>2</sub>(<i>η</i><...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Molbank |
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| Online Access: | https://www.mdpi.com/1422-8599/2020/3/M1145 |
| _version_ | 1797563277040943104 |
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| author | Javier Francos Alba E. Díaz-Álvarez Victorio Cadierno |
| author_facet | Javier Francos Alba E. Díaz-Álvarez Victorio Cadierno |
| author_sort | Javier Francos |
| collection | DOAJ |
| description | The synthesis of two novel enol esters, namely hex-1-en-2-yl indole-2-carboxylate and hex-1-en-2-yl 1-(hex-1-en-2-yl)-indole-2-carboxylate, is presented. Both compounds were generated by addition of indole-2-carboxylic acid to 1-hexyne employing [RuCl<sub>2</sub>(<i>η</i><sup>6</sup>-<i>p</i>-cymene)(PPh<sub>3</sub>)] and [AuCl(PPh<sub>3</sub>)]/AgPF<sub>6</sub>, respectively, as catalysts. |
| first_indexed | 2024-03-10T18:41:19Z |
| format | Article |
| id | doaj.art-31984c3d8efb4c9ab192742ac02a073d |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-03-10T18:41:19Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-31984c3d8efb4c9ab192742ac02a073d2023-11-20T05:49:19ZengMDPI AGMolbank1422-85992020-07-0120203M114510.3390/M1145Catalytic Addition of Indole-2-Carboxylic Acid to 1-HexyneJavier Francos0Alba E. Díaz-Álvarez1Victorio Cadierno2Laboratorio de Compuestos Organometálicos y Catálisis (Unidad Asociada al CSIC), Departamento de Química Orgánica e Inorgánica, Facultad de Química, Universidad de Oviedo, Julián Clavería 8, E-33006 Oviedo, SpainLaboratorio de Compuestos Organometálicos y Catálisis (Unidad Asociada al CSIC), Departamento de Química Orgánica e Inorgánica, Facultad de Química, Universidad de Oviedo, Julián Clavería 8, E-33006 Oviedo, SpainLaboratorio de Compuestos Organometálicos y Catálisis (Unidad Asociada al CSIC), Departamento de Química Orgánica e Inorgánica, Facultad de Química, Universidad de Oviedo, Julián Clavería 8, E-33006 Oviedo, SpainThe synthesis of two novel enol esters, namely hex-1-en-2-yl indole-2-carboxylate and hex-1-en-2-yl 1-(hex-1-en-2-yl)-indole-2-carboxylate, is presented. Both compounds were generated by addition of indole-2-carboxylic acid to 1-hexyne employing [RuCl<sub>2</sub>(<i>η</i><sup>6</sup>-<i>p</i>-cymene)(PPh<sub>3</sub>)] and [AuCl(PPh<sub>3</sub>)]/AgPF<sub>6</sub>, respectively, as catalysts.https://www.mdpi.com/1422-8599/2020/3/M1145enol estershydro-oxycarbonylation reactionshydroamination reactionsruthenium catalystsgold catalysts |
| spellingShingle | Javier Francos Alba E. Díaz-Álvarez Victorio Cadierno Catalytic Addition of Indole-2-Carboxylic Acid to 1-Hexyne Molbank enol esters hydro-oxycarbonylation reactions hydroamination reactions ruthenium catalysts gold catalysts |
| title | Catalytic Addition of Indole-2-Carboxylic Acid to 1-Hexyne |
| title_full | Catalytic Addition of Indole-2-Carboxylic Acid to 1-Hexyne |
| title_fullStr | Catalytic Addition of Indole-2-Carboxylic Acid to 1-Hexyne |
| title_full_unstemmed | Catalytic Addition of Indole-2-Carboxylic Acid to 1-Hexyne |
| title_short | Catalytic Addition of Indole-2-Carboxylic Acid to 1-Hexyne |
| title_sort | catalytic addition of indole 2 carboxylic acid to 1 hexyne |
| topic | enol esters hydro-oxycarbonylation reactions hydroamination reactions ruthenium catalysts gold catalysts |
| url | https://www.mdpi.com/1422-8599/2020/3/M1145 |
| work_keys_str_mv | AT javierfrancos catalyticadditionofindole2carboxylicacidto1hexyne AT albaediazalvarez catalyticadditionofindole2carboxylicacidto1hexyne AT victoriocadierno catalyticadditionofindole2carboxylicacidto1hexyne |