Phenylarsine Oxide Can Induce the Arsenite-Resistance Mutant PML Protein Solubility Changes

Phenylarsine Oxide Can Induce the Arsenite-Resistance Mutant PML Protein Solubility Changes

Arsenic trioxide (As2O3) has recently become one of the most effective drugs for treatment of patient with acute promyelocytic leukemia (APL), and its molecular mechanism has also been largely investigated. However, it has been reported that As2O3 resistant patients are frequently found in relapsed...

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Bibliographic Details
Main Authors:	Yu Han Jiang, Ye Jia Chen, Chao Wang, Yong Fei Lan, Chang Yang, Qian Qian Wang, Liaqat Hussain, Yasen Maimaitiying, Islam Khairul, Hua Naranmandura
Format:	Article
Language:	English
Published:	MDPI AG 2017-01-01
Series:	International Journal of Molecular Sciences
Subjects:	arsenite acute promyelocytic leukemia arsenic trioxide monomethylarsonous acid dimethylarsinous acid phenylarsine oxide trivalent arsenicals
Online Access:	http://www.mdpi.com/1422-0067/18/2/247

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