Angioedema: Classification, management and emerging therapies for the perioperative physician
Angioedema is a rare condition which manifests as sudden localised, non-pitting swelling of certain body parts including skin and mucous membranes. It is vital that anaesthesiologists understand this condition, as it may present suddenly in the perioperative period with airway compromise. To identif...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Indian Journal of Anaesthesia |
| Subjects: | |
| Online Access: | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2016;volume=60;issue=8;spage=534;epage=541;aulast=Misra |
| _version_ | 1819050067914391552 |
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| author | Lopa Misra Narjeet Khurmi Terrence L Trentman |
| author_facet | Lopa Misra Narjeet Khurmi Terrence L Trentman |
| author_sort | Lopa Misra |
| collection | DOAJ |
| description | Angioedema is a rare condition which manifests as sudden localised, non-pitting swelling of certain body parts including skin and mucous membranes. It is vital that anaesthesiologists understand this condition, as it may present suddenly in the perioperative period with airway compromise. To identify literature for this review, the authors searched the PubMed, Medline, Embase, Scopus and Web of Science databases for English language articles covering a 10-year period, 2006 through 2016. Angioedema can be either mast-cell mediated or bradykinin-induced. Older therapies for histaminergic symptoms are well known to anaesthesiologists (e.g., adrenaline, anti-histamines and steroids), whereas older therapies for bradykinin-induced symptoms include plasma and attenuated androgens. New classes of drugs for bradykinin-induced symptoms are now available, including anti-bradykinin, plasma kallikrein inhibitor and C1 esterase inhibitors. These can be used prophylactically or as rescue medications. Anaesthesiologists are in a unique position to coordinate perioperative care for this complex group of patients. |
| first_indexed | 2024-12-21T11:42:10Z |
| format | Article |
| id | doaj.art-319e4ae6dc314a6d9536e9efb6a13095 |
| institution | Directory Open Access Journal |
| issn | 0019-5049 |
| language | English |
| last_indexed | 2024-12-21T11:42:10Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Anaesthesia |
| spelling | doaj.art-319e4ae6dc314a6d9536e9efb6a130952022-12-21T19:05:16ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50492016-01-0160853454110.4103/0019-5049.187776Angioedema: Classification, management and emerging therapies for the perioperative physicianLopa MisraNarjeet KhurmiTerrence L TrentmanAngioedema is a rare condition which manifests as sudden localised, non-pitting swelling of certain body parts including skin and mucous membranes. It is vital that anaesthesiologists understand this condition, as it may present suddenly in the perioperative period with airway compromise. To identify literature for this review, the authors searched the PubMed, Medline, Embase, Scopus and Web of Science databases for English language articles covering a 10-year period, 2006 through 2016. Angioedema can be either mast-cell mediated or bradykinin-induced. Older therapies for histaminergic symptoms are well known to anaesthesiologists (e.g., adrenaline, anti-histamines and steroids), whereas older therapies for bradykinin-induced symptoms include plasma and attenuated androgens. New classes of drugs for bradykinin-induced symptoms are now available, including anti-bradykinin, plasma kallikrein inhibitor and C1 esterase inhibitors. These can be used prophylactically or as rescue medications. Anaesthesiologists are in a unique position to coordinate perioperative care for this complex group of patients.http://www.ijaweb.org/article.asp?issn=0019-5049;year=2016;volume=60;issue=8;spage=534;epage=541;aulast=MisraAirwayangioedemabradykininC1 esterase inhibitorhistamine |
| spellingShingle | Lopa Misra Narjeet Khurmi Terrence L Trentman Angioedema: Classification, management and emerging therapies for the perioperative physician Indian Journal of Anaesthesia Airway angioedema bradykinin C1 esterase inhibitor histamine |
| title | Angioedema: Classification, management and emerging therapies for the perioperative physician |
| title_full | Angioedema: Classification, management and emerging therapies for the perioperative physician |
| title_fullStr | Angioedema: Classification, management and emerging therapies for the perioperative physician |
| title_full_unstemmed | Angioedema: Classification, management and emerging therapies for the perioperative physician |
| title_short | Angioedema: Classification, management and emerging therapies for the perioperative physician |
| title_sort | angioedema classification management and emerging therapies for the perioperative physician |
| topic | Airway angioedema bradykinin C1 esterase inhibitor histamine |
| url | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2016;volume=60;issue=8;spage=534;epage=541;aulast=Misra |
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