The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies.

The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies.

Curcumin (CUR) is the major constituent of the rhizomes of Curcuma longa and has been widely investigated for its chemotherapeutic properties. The well-known activity of CUR against Leishmania sp., Trypanosoma brucei and Plasmodium falciparum led us to investigate its activity against Trypanosoma cr...

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Main Authors:	Vitor Sueth-Santiago, Julliane de B B Moraes, Eliomara Sousa Sobral Alves, Marcos André Vannier-Santos, Célio G Freire-de-Lima, Rosane N Castro, Gustavo Peron Mendes-Silva, Catarina de Nigris Del Cistia, Luma Godoy Magalhães, Adriano Defini Andricopulo, Carlos Mauricio R Sant Anna, Debora Decoté-Ricardo, Marco Edilson Freire de Lima
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2016-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC5033595?pdf=render

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