Chlamydia trachomatis Infection Impairs MHC-I Intracellular Trafficking and Antigen Cross-Presentation by Dendritic Cells

Chlamydia trachomatis Infection Impairs MHC-I Intracellular Trafficking and Antigen Cross-Presentation by Dendritic Cells

During cross-presentation, exogenous antigens (i.e. intracellular pathogens or tumor cells) are internalized and processed within the endocytic system and also by the proteasome in the cytosol. Then, antigenic peptides are associated with Major Histocompatibility Complex (MHC) class I molecules and...

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Bibliographic Details
Main Authors: Diego Del Balzo, Anahí Capmany, Ignacio Cebrian, María Teresa Damiani
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
cross-presentation
MHC-I recycling
Chlamydia trachomatis
dendritic cells
endocytic recycling compartment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.662096/full

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