Progressive Posterior Encephalopathy Syndrome Related with Drug-refractory Hypertension in a Patient with Pheochromocytoma

Background: Posterior reversible encephalopathy syndrome (PRES) is a neuroradiological syndrome characterized by headache, altered mental status, visual disturbance, and seizures with diagnostic MRI features, especially in the territories of posterior circulation. Reversibility of clinical and radio...

Full description

Bibliographic Details
Main Authors: Yu Jin Jung, Youngnam Kwon, Sung Hyuk Heo, Kyoung Jin Hwang, Dae-Il Chang
Format: Article
Language:English
Published: The Korean Neurocritical Care Society 2014-12-01
Series:Journal of Neurocritical Care
Subjects:
Online Access:http://www.e-jnc.org/upload/pdf/jnc-7-2-141.pdf
_version_ 1819127842208743424
author Yu Jin Jung
Youngnam Kwon
Sung Hyuk Heo
Kyoung Jin Hwang
Dae-Il Chang
author_facet Yu Jin Jung
Youngnam Kwon
Sung Hyuk Heo
Kyoung Jin Hwang
Dae-Il Chang
author_sort Yu Jin Jung
collection DOAJ
description Background: Posterior reversible encephalopathy syndrome (PRES) is a neuroradiological syndrome characterized by headache, altered mental status, visual disturbance, and seizures with diagnostic MRI features, especially in the territories of posterior circulation. Reversibility of clinical and radiologic findings is generally regarded as a defining feature of PRES. Case Report: A 72-year old man who had a history of hypertension presented with subacute and progressive visual disturbance, dizziness, limb ataxia, and finally non-convulsive status epilepticus. Magnetic resonance imaging (MRI) showed extensive lesions in bilateral parieto-occipital cortex and subcortex. Due to his marked fluctuation of blood pressure, we detected a pheochromocytoma of left adrenal gland. In spite of administration with several types of antihypertensive medication, the patient presented with clinical deterioration, leading to death. MRI demonstrated the progression of lesions. Conclusion: This case report highlights the clinical and radiological progression of posterior encephalopathy syndrome caused by pheochromocytoma despite appropriate treatment of blood pressure.
first_indexed 2024-12-22T08:18:21Z
format Article
id doaj.art-31ac434e49e5449db5230cc076a1c10c
institution Directory Open Access Journal
issn 2005-0348
language English
last_indexed 2024-12-22T08:18:21Z
publishDate 2014-12-01
publisher The Korean Neurocritical Care Society
record_format Article
series Journal of Neurocritical Care
spelling doaj.art-31ac434e49e5449db5230cc076a1c10c2022-12-21T18:32:49ZengThe Korean Neurocritical Care SocietyJournal of Neurocritical Care2005-03482014-12-017214114410.18700/jnc.2014.7.2.141139Progressive Posterior Encephalopathy Syndrome Related with Drug-refractory Hypertension in a Patient with PheochromocytomaYu Jin Jung0Youngnam Kwon1Sung Hyuk Heo2Kyoung Jin Hwang3Dae-Il Chang4 Department of Neurology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea Department of Neurology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea Department of Neurology, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea Department of Neurology, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea Department of Neurology, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, KoreaBackground: Posterior reversible encephalopathy syndrome (PRES) is a neuroradiological syndrome characterized by headache, altered mental status, visual disturbance, and seizures with diagnostic MRI features, especially in the territories of posterior circulation. Reversibility of clinical and radiologic findings is generally regarded as a defining feature of PRES. Case Report: A 72-year old man who had a history of hypertension presented with subacute and progressive visual disturbance, dizziness, limb ataxia, and finally non-convulsive status epilepticus. Magnetic resonance imaging (MRI) showed extensive lesions in bilateral parieto-occipital cortex and subcortex. Due to his marked fluctuation of blood pressure, we detected a pheochromocytoma of left adrenal gland. In spite of administration with several types of antihypertensive medication, the patient presented with clinical deterioration, leading to death. MRI demonstrated the progression of lesions. Conclusion: This case report highlights the clinical and radiological progression of posterior encephalopathy syndrome caused by pheochromocytoma despite appropriate treatment of blood pressure.http://www.e-jnc.org/upload/pdf/jnc-7-2-141.pdfHypertensive encephalopathyPheochromocytomaStatus epilepticus
spellingShingle Yu Jin Jung
Youngnam Kwon
Sung Hyuk Heo
Kyoung Jin Hwang
Dae-Il Chang
Progressive Posterior Encephalopathy Syndrome Related with Drug-refractory Hypertension in a Patient with Pheochromocytoma
Journal of Neurocritical Care
Hypertensive encephalopathy
Pheochromocytoma
Status epilepticus
title Progressive Posterior Encephalopathy Syndrome Related with Drug-refractory Hypertension in a Patient with Pheochromocytoma
title_full Progressive Posterior Encephalopathy Syndrome Related with Drug-refractory Hypertension in a Patient with Pheochromocytoma
title_fullStr Progressive Posterior Encephalopathy Syndrome Related with Drug-refractory Hypertension in a Patient with Pheochromocytoma
title_full_unstemmed Progressive Posterior Encephalopathy Syndrome Related with Drug-refractory Hypertension in a Patient with Pheochromocytoma
title_short Progressive Posterior Encephalopathy Syndrome Related with Drug-refractory Hypertension in a Patient with Pheochromocytoma
title_sort progressive posterior encephalopathy syndrome related with drug refractory hypertension in a patient with pheochromocytoma
topic Hypertensive encephalopathy
Pheochromocytoma
Status epilepticus
url http://www.e-jnc.org/upload/pdf/jnc-7-2-141.pdf
work_keys_str_mv AT yujinjung progressiveposteriorencephalopathysyndromerelatedwithdrugrefractoryhypertensioninapatientwithpheochromocytoma
AT youngnamkwon progressiveposteriorencephalopathysyndromerelatedwithdrugrefractoryhypertensioninapatientwithpheochromocytoma
AT sunghyukheo progressiveposteriorencephalopathysyndromerelatedwithdrugrefractoryhypertensioninapatientwithpheochromocytoma
AT kyoungjinhwang progressiveposteriorencephalopathysyndromerelatedwithdrugrefractoryhypertensioninapatientwithpheochromocytoma
AT daeilchang progressiveposteriorencephalopathysyndromerelatedwithdrugrefractoryhypertensioninapatientwithpheochromocytoma