A functional reference map of the RNF8 interactome in cancer

A functional reference map of the RNF8 interactome in cancer

Abstract Background RNF8 is an E3 ligase identified as a critical DNA damage-responsive protein. Recently, multiple reports have shown that RNF8 could be used as an important therapeutic target for cancer chemo/radiotherapy. However, the understanding of RNF8 remains limited due to the lack of its i...

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Bibliographic Details
Main Authors: Chuanyang Liu, Jingyu Kuang, Yuxuan Wang, Ting Duan, Lu Min, Chenyu Lu, Tianyi Zhang, Ruifen Chen, Ying Wu, Lingyun Zhu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Biology Direct
Subjects:
Pancancer analysis
RNF8
Interactome
YBX1
Ubiquitination
Online Access:https://doi.org/10.1186/s13062-022-00331-z

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