Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix
<p>Abstract</p> <p>Introduction</p> <p>Pulmonary metastasis presenting as lymphangitic carcinomatosis arising from squamous cell carcinoma (SCC) of the cervix is a rare event. Poorly represented in the literature, this event is associated with a) difficulty in accurate...
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| Format: | Article |
| Language: | English |
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BMC
2010-12-01
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| Series: | World Journal of Surgical Oncology |
| Online Access: | http://www.wjso.com/content/8/1/107 |
| _version_ | 1818334903032348672 |
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| author | Senger Jenna-Lynn B Kanthan Rani Diudea Dana |
| author_facet | Senger Jenna-Lynn B Kanthan Rani Diudea Dana |
| author_sort | Senger Jenna-Lynn B |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Introduction</p> <p>Pulmonary metastasis presenting as lymphangitic carcinomatosis arising from squamous cell carcinoma (SCC) of the cervix is a rare event. Poorly represented in the literature, this event is associated with a) difficulty in accurate diagnosis, b) grave prognosis, and the c) lack of recognized predisposing risk factors.</p> <p>Case Report</p> <p>A 50 year-old female presented at our practice with a three-month history of a productive cough associated with dyspnoea and shortness of breath. A chest x-ray and computed tomography (CT) scan revealed multiple bilateral patchy areas with subsegmental atelectasis in both lungs which was investigated with a bronchoscopy, left thoracoscopy, and a left lung biopsy. Pathological examination of the wedge biopsy of the left upper lobe revealed neoplastic sheets of cell disturbed along the septal vessels, perivascular/peribronchial lymphatics, and the subpleural lymphatics. This lymphangitic carcinomatosis was confirmed to be metastatic from SCC of the cervix that had been diagnosed and treated two years ago. She was treated with systemic Carbo/Taxol chemotherapy and corticosteroids as a palliative measure. Despite temporary improvement, she died 13 months later.</p> <p>Conclusion</p> <p>Pulmonary lymphangitic carcinomatosis is a rare manifestation of metastatic SCC of the cervix. As clinical presentations including radiographic imaging mimics other pulmonary entities, accurate diagnosis remains a challenge. Increased clinical awareness of such patterns of metastases in cervical cancer supported by accurate pathological diagnosis is imperative to guide appropriate therapy in these patients.</p> |
| first_indexed | 2024-12-13T14:14:55Z |
| format | Article |
| id | doaj.art-31b3b7070cf84dc182d98a84b8736fe3 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-13T14:14:55Z |
| publishDate | 2010-12-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-31b3b7070cf84dc182d98a84b8736fe32022-12-21T23:42:21ZengBMCWorld Journal of Surgical Oncology1477-78192010-12-018110710.1186/1477-7819-8-107Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervixSenger Jenna-Lynn BKanthan RaniDiudea Dana<p>Abstract</p> <p>Introduction</p> <p>Pulmonary metastasis presenting as lymphangitic carcinomatosis arising from squamous cell carcinoma (SCC) of the cervix is a rare event. Poorly represented in the literature, this event is associated with a) difficulty in accurate diagnosis, b) grave prognosis, and the c) lack of recognized predisposing risk factors.</p> <p>Case Report</p> <p>A 50 year-old female presented at our practice with a three-month history of a productive cough associated with dyspnoea and shortness of breath. A chest x-ray and computed tomography (CT) scan revealed multiple bilateral patchy areas with subsegmental atelectasis in both lungs which was investigated with a bronchoscopy, left thoracoscopy, and a left lung biopsy. Pathological examination of the wedge biopsy of the left upper lobe revealed neoplastic sheets of cell disturbed along the septal vessels, perivascular/peribronchial lymphatics, and the subpleural lymphatics. This lymphangitic carcinomatosis was confirmed to be metastatic from SCC of the cervix that had been diagnosed and treated two years ago. She was treated with systemic Carbo/Taxol chemotherapy and corticosteroids as a palliative measure. Despite temporary improvement, she died 13 months later.</p> <p>Conclusion</p> <p>Pulmonary lymphangitic carcinomatosis is a rare manifestation of metastatic SCC of the cervix. As clinical presentations including radiographic imaging mimics other pulmonary entities, accurate diagnosis remains a challenge. Increased clinical awareness of such patterns of metastases in cervical cancer supported by accurate pathological diagnosis is imperative to guide appropriate therapy in these patients.</p>http://www.wjso.com/content/8/1/107 |
| spellingShingle | Senger Jenna-Lynn B Kanthan Rani Diudea Dana Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix World Journal of Surgical Oncology |
| title | Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix |
| title_full | Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix |
| title_fullStr | Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix |
| title_full_unstemmed | Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix |
| title_short | Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix |
| title_sort | pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix |
| url | http://www.wjso.com/content/8/1/107 |
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