Following the Clues: Usefulness of Biomarkers of Neuroinflammation and Neurodegeneration in the Investigation of HTLV-1-Associated Myelopathy Progression

Following the Clues: Usefulness of Biomarkers of Neuroinflammation and Neurodegeneration in the Investigation of HTLV-1-Associated Myelopathy Progression

Human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurodegenerative disease due to axonal damage of the corticospinal secondary to an inflammatory response against infected T-cells. In the present work, we aimed to evaluate biomarkers of neu...

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Bibliographic Details
Main Authors: Flávia dos Santos Souza, Nicole Lardini Freitas, Yago Côrtes Pinheiro Gomes, Rafael Carvalho Torres, Juliana Echevarria-Lima, Isaac Lima da Silva-Filho, Ana Claudia Celestino Bezerra Leite, Marco Antonio Sales Dantas de Lima, Marcus Tulius Teixeira da Silva, Abelardo de Queiroz Campos Araújo, Otávio Melo Espíndola
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
HTLV-1
biomarkers
neuroinflammation
neopterin
chemokines
Tau protein
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.737941/full

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