Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids
The biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety.
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2016-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms13083 |
| _version_ | 1818405241888964608 |
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| author | Yijun Yan Jing Yang Zhiyin Yu Mingming Yu Ya-Tuan Ma Li Wang Can Su Jianying Luo Geoffrey P. Horsman Sheng-Xiong Huang |
| author_facet | Yijun Yan Jing Yang Zhiyin Yu Mingming Yu Ya-Tuan Ma Li Wang Can Su Jianying Luo Geoffrey P. Horsman Sheng-Xiong Huang |
| author_sort | Yijun Yan |
| collection | DOAJ |
| description | The biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety. |
| first_indexed | 2024-12-14T08:52:55Z |
| format | Article |
| id | doaj.art-31b58558e98149e0865282c772e6c8b2 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T08:52:55Z |
| publishDate | 2016-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-31b58558e98149e0865282c772e6c8b22022-12-21T23:09:00ZengNature PortfolioNature Communications2041-17232016-10-017111010.1038/ncomms13083Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloidsYijun Yan0Jing Yang1Zhiyin Yu2Mingming Yu3Ya-Tuan Ma4Li Wang5Can Su6Jianying Luo7Geoffrey P. Horsman8Sheng-Xiong Huang9State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesDepartment of Chemistry & Biochemistry, Wilfrid Laurier UniversityState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of SciencesThe biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety.https://doi.org/10.1038/ncomms13083 |
| spellingShingle | Yijun Yan Jing Yang Zhiyin Yu Mingming Yu Ya-Tuan Ma Li Wang Can Su Jianying Luo Geoffrey P. Horsman Sheng-Xiong Huang Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids Nature Communications |
| title | Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids |
| title_full | Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids |
| title_fullStr | Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids |
| title_full_unstemmed | Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids |
| title_short | Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids |
| title_sort | non enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids |
| url | https://doi.org/10.1038/ncomms13083 |
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