Comparative study on clinically latent aggressiveness inoutpatients with schizophrenia treated with classical antipsychotics and with risperidone

Objective: The use of neuroleptics causes not only regression of psychotic symptoms; neuroleptics affect also the patients’ mental state which is changing not only due to medications effects but also secondarily, as a result of regression of psychotic symptoms. The aim of this study was evaluation...

Full description

Bibliographic Details
Main Authors: Konstantinos Tsirigotis, Wojciech Gruszczyński
Format: Article
Language:English
Published: Medical Communications Sp. z o.o. 2014-03-01
Series:Psychiatria i Psychologia Kliniczna
Subjects:
Online Access:http://www.psychiatria.com.pl/index.php/wydawnictwa/2014-vol-14-no-1/comparative-study-on-clinically-latent-aggressiveness-in-outpatients-with-schizophrenia-treated-with-classical-antipsychotics-and-with-risperidone?aid=346
Description
Summary:Objective: The use of neuroleptics causes not only regression of psychotic symptoms; neuroleptics affect also the patients’ mental state which is changing not only due to medications effects but also secondarily, as a result of regression of psychotic symptoms. The aim of this study was evaluation of subjectively felt “silent” (clinically latent) hostility and aggressiveness in patients with paranoid schizophrenia treated with typical neuroleptics and risperidone. Material and methods: Sixty patients (30 patients treated with typical neuroleptics and the other 30 – with risperidone) were examined with the Polish version of the following tools: Minnesota Multiphasic Personality Inventory (MMPI), Adjective Check List (ACL) and Stern Activities Index (SAI). Results: The statistical analysis of the obtained results yielded many statistically significant differences within the intensity of hostility and aggressiveness in the examined groups. Conclusions: The results of this study showed a higher severity of psychological and personality problems in patients treated with typical neuroleptics, as compared to those treated with risperidone. In patients with paranoid schizophrenia treated with risperidone a lower severity of psychopathological, especially schizophrenic and paranoid, symptoms and lower hostility and aggressiveness were found. Considering that risperidone improves verbal functions, it can be assumed that this entails an improvement in the patients’ communicative competences, thereby improving also their interpersonal relationships. The results of this study indicate a higher susceptibility of people in this group to social influences and less hostility and negativity experienced by them.
ISSN:1644-6313
2451-0645